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Showing 61-80 of 172 Resources
  • Dog Genomics and Dogs as Model Organisms

    Dog Genomics and Dogs as Model Organisms

    Science Talks

    (28 min 54 sec) Dr. Elinor Karlsson discusses her work with dogs as a model organism for genomic studies.

  • Genomic Medicine, Autism, and Cancer

    Genomic Medicine, Autism, and Cancer

    Science Talks

    (37 min 26 sec) A student discussion with the lecturers of the 2013 Holiday Lectures on Science.

  • From Cancer Genomics to Cancer Drugs

    From Cancer Genomics to Cancer Drugs

    Science Talks

    (58 min 46 sec) Genetic data from a large number of tumor types reveal commonly mutated genes and uncover connections between different types of cancer.

  • Decoding the Autism Puzzle

    Decoding the Autism Puzzle

    Science Talks

    (58 min 5 sec) Over the past decade, the application of advanced DNA sequencing techniques has greatly increased our understanding of the genetic basis of autism.

  • Cancer As a Genetic Disease

    Cancer As a Genetic Disease

    Science Talks

    (58 min 33 sec) Understanding that cancer is caused by mutations in genes that regulate cell proliferation has led to the development of targeted drug therapies.

  • Sizing Up the Brain Gene By Gene

    Sizing Up the Brain Gene By Gene

    Science Talks

    (59 min 32 sec) Recent advances in DNA sequencing technology have led to a better understanding of the many genes that play a role in brain development.

  • Gleevec-Resistant Form of Kinase BCR-ABL

    Gleevec-Resistant Form of Kinase BCR-ABL

    Animations

    (2 min 14 sec) Mutations in the BCR-ABL gene can cause resistance to Gleevec, but another drug, dasatinib, can be used instead.

  • Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Animations

    (3 min 31 sec) The drug Gleevec binds to and inactivates BCR-ABL, a mutant kinase that causes chronic myeloid leukemia. 

  • Film Guides: The Double Helix

    Film Guides: The Double Helix

    Film Guides

    The following classroom-ready resources complement The Double Helix. This short film describes the evidence that led James Watson and Francis Crick to the discovery of the double-helical structure of DNA and how the structure immediately revealed how genetic information is stored and inherited.

  • Lactose Intolerance: Fact or Fiction

    Lactose Intolerance: Fact or Fiction

    Activities

    Students evaluate and discuss several statements about lactose intolerance and evolution before and after watching the film. Also available in Spanish.

  • The Double Helix

    The Double Helix

    Short Films

    (16 min 53 sec) The Double Helix is the story of the scientists and evidence involved in one of the most important scientific quests of the 20th century: the discovery of the structure of DNA. Also available in Spanish.

  • The Origin of Species: Lizards in an Evolutionary Tree

    The Origin of Species: Lizards in an Evolutionary Tree

    Short Films

    (17 min 45 sec) In the Caribbean islands, adaptation to several common habitats has led to a large adaptive radiation with interesting examples of convergent evolution. Also available in Spanish.

  • Meet Charles Sawyers

    Meet Charles Sawyers

    Clips

    (2 min 27 sec) Dr. Sawyers is an HHMI investigator who has contributed to the development of drugs that target leukemia and prostate cancer. 

  • Meet Chris Walsh

    Meet Chris Walsh

    Clips

    (2 min 3 sec) Dr. Walsh is an HHMI investigator whose research focuses on understanding the genes involved in the development and function of the human brain.

  • Genetic Mutations and Disease

    Genetic Mutations and Disease

    Posters

    The poster for the 2013 Holiday Lectures on Science, Medicine in the Genomic Era, illustrates the difference between germline and somatic cell mutations.

  • Medicine in the Genomic Era

    Medicine in the Genomic Era

    Science Talks

    In the 2013 Holiday Lectures on Science, leading medical researchers explain how advances in genomics are revolutionizing their work, leading to a better understanding of disease and to improved treatments.

  • Got Lactase? Blood Glucose Data Analysis

    Got Lactase? Blood Glucose Data Analysis

    Activities

    Students interpret the results of two different tests for lactase persistence.

  • Using Genetic Crosses to Analyze a Stickleback Trait

    Using Genetic Crosses to Analyze a Stickleback Trait

    Activities

    A hands-on activity in which students analyze the results of genetic crosses between stickleback fish with different traits.

  • Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

    Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

    Activities

    A hands-on activity in which students interpret molecular diagrams and build physical models of eukaryotic gene regulation.

  • Teacher Guide: Gene Regulation

    Teacher Guide: Gene Regulation

    Resource Guides

    Topics include: Gene regulation mechanisms and examples, gene regulation and human disease, and RNA interference.

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