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Showing 1-60 of 190 Resources
  • Sex Verification Testing of Athletes

    Sex Verification Testing of Athletes

    Click & Learn

    This interactive explores the biology of sex determination and development in humans, set against the backdrop of the different sex testing policies implemented throughout sports history.

  • Developing an Explanation for Mouse Fur Color

    Developing an Explanation for Mouse Fur Color

    Activity

    Students collect and analyze evidence for each of the major conditions for evolution by natural selection to develop an explanation for how populations change over time. Also available in Spanish.

  • Cystic Fibrosis Mechanism and Treatment

    Cystic Fibrosis Mechanism and Treatment

    Animation

    (2 min 31 sec) Mutations in the CFTR gene, which encodes a transmembrane ion channel, cause mucus buildup in the airways of patients with cystic fibrosis.

  • CRISPR-Cas 9 Mechanism & Applications

    CRISPR-Cas 9 Mechanism & Applications

    Click & Learn

    Explore this dynamic interactive to learn the basic principles of how this revolutionary tool works and the many ways in which scientists are using it in their research.

  • Pelvic Evolution in Sticklebacks

    Pelvic Evolution in Sticklebacks

    Data Point

    Scientists used SNP genotyping in populations of freshwater stickleback fish to determine the genetic mutations responsible for the impaired development of pelvises and spines.

  • Solving Crimes with the NECROBIOME

    Solving Crimes with the NECROBIOME

    Feature Film

    (7 min 10 sec) We can’t talk to the dead, but in their own way, the dead can speak to us.

  • Central Dogma Card Activity

    Central Dogma Card Activity

    Activity

    In this hands-on activity students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat genetic disease.

  • Monkey Social Status and Immune Response

    Monkey Social Status and Immune Response

    Data Point

    Scientists studied how the dominance ranking of female rhesus macaques living in social groups affected the expression of genes linked to immune response

  • Film Guide for Genes as Medicine

    Film Guide for Genes as Medicine

    Film Guide

    The following classroom-ready resources complement the film Genes as Medicine. It tells the story of the successes and challenges that led to the development of the first FDA-approved gene therapy for a genetic disease.

  • The Search for a Mutated Gene

    The Search for a Mutated Gene

    Scientists at Work

    (8 min 54 sec) How do you identify the disease-causing mutation in a patient with an inherited disease? This video illustrates the steps involved—testing for genes that are the “usual suspects,” searching for mutations in novel genes, and assessing links between genotype and phenotype.

  • Genes as Medicine

    Genes as Medicine

    Short Film

    (17 min 16 sec) Watch the story of how gene therapy restored the sight of a nearly-blind young patient. Told from the perspective of two researchers who spent over 25 years working to develop this breakthrough technology, this short film chronicles their successes and challenges, and illustrates how the method works to treat inherited conditions.

  • Stalking the Genetic Basis of a Trait

    Stalking the Genetic Basis of a Trait

    Activity

    In this activity students analyze data on the expression of the tb1 gene and use it to formulate an explanation as to how a specific difference in the corn version of the gene explains the phenotype of less branching.

  • Central Dogma and Genetic Medicine

    Central Dogma and Genetic Medicine

    Click & Learn

    This interactive uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat genetic diseases.

  • Patterns in the Distribution of Lactase Persistence

    Patterns in the Distribution of Lactase Persistence

    Activity

    Students explore the geographic distribution of lactase persistence around the world by analyzing real data collected by scientists.

  • Teacher Guides

    Teacher Guides

    Collection

    Designed by educators, BioInteractive’s teacher guides will help you select BioInteractive resources aligned to specific topics and standards, including the AP® Biology Curriculum Framework.

  • Think Like a Scientist: Natural Selection in an Outbreak

    Think Like a Scientist: Natural Selection in an Outbreak

    Scientists at Work

    (7 min 29 sec) This video brings us to the front lines of the 2013–2015 Ebola outbreak in west Africa and explains how scientists monitored the evolution of the virus by analyzing its genome.

  • DNA Profiling Activity

    DNA Profiling Activity

    Activity

    This multi-part lesson is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world. 

  • Genetic Mutations and Disease Interactive

    Genetic Mutations and Disease Interactive

    Click & Learn

    This interactive focuses on the roles of germline and somatic cell mutations in human disease. It supports the 2013 Holiday Lectures on Science, Medicine in the Genomic Era.

  • Genetically Modified Mosquitoes

    Genetically Modified Mosquitoes

    Scientists at Work

    (8 min 35 sec) Learn the process by which a line of genetically modified mosquitoes was engineered to reduce populations of Aedes aegypti mosquitoes in the wild.

  • Understanding Variation

    Understanding Variation

    Activity

    This lesson complements the film The Biology of Skin Color and discusses variation in human skin color and polygenic inheritance. Also available in Spanish.

  • Zebrafish and Skin Color

    Zebrafish and Skin Color

    Activity

    This lesson complements the film The Biology of Skin Color and explores how experimental work in zebrafish led to a better understanding of the role of the gene SLC24A5 in human skin color.

  • Alzheimer’s Disease: Piecing Together the Evidence

    Alzheimer’s Disease: Piecing Together the Evidence

    Click & Learn

    This interactive explores evidence from brain anatomy, tissue histology, and genetic studies to reveal possible targets for the treatment of Alzheimer’s disease.

  • Using Genetic Evidence to Identify Ivory Poaching Hotspots

    Using Genetic Evidence to Identify Ivory Poaching Hotspots

    Data Point

    A team of scientists analyzed the DNA from seized ivory to determine where the ivory from poached elephants came from.

  • CSI Wildlife

    CSI Wildlife

    Click & Learn

    In this interactive, students use DNA profiling, or fingerprinting, to solve two cases of elephant poaching. In the process they will learn about genetic markers, PCR, gel electrophoresis, allele frequencies, and population genetics.

  • Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease

    Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease

    Data Point

    A team of scientists built a pedigree of a large extended family in Antioquia, Colombia, that has a high prevalence of early-onset familial Alzheimer’s disease due to a mutation in the PSEN1 gene. Worksheets also available in Spanish.

  • Stickleback Film with Quiz

    Stickleback Film with Quiz

    Interactive Video

    (15 min 27 sec) Embedded quiz modules test students’ understanding as they watch a short film that explains how stickleback fish let scientists study evolution in action, identify key genes, and peer deep into the evolutionary past.

  • Lactase Film with Quiz

    Lactase Film with Quiz

    Interactive Video

    (14 min 52 sec) Embedded quiz modules test students’ understanding as they watch a short film that explores the evolution of the ability to digest lactose as adults (lactose tolerance) and the genetic changes associated with the trait.

  • Identifying Autism Genes by Tracking Gene Mutations

    Identifying Autism Genes by Tracking Gene Mutations

    Data Point

    A team of scientists used homozygosity mapping to map SNPs on chromosome 3 in a family with an autistic son to identify a likely gene that caused the disorder.

  • The Teosinte Hypothesis

    The Teosinte Hypothesis

    Activity

    In this lesson, students work through the mathematics and concepts behind George Beadle’s claim that teosinte is the wild ancestor of maize. Also available in Spanish.

  • Skin Color Interactive Video

    Skin Color Interactive Video

    Interactive Video

    (18 min 58 sec) Embedded quiz modules test students’ understanding as they watch a short film that explores the evidence for the evolution of the variation in skin color among human populations.

  • Popped Secret Film with Quiz

    Popped Secret Film with Quiz

    Interactive Video

    (17 min 51 sec) Embedded quiz modules test students’ understanding as they watch a short film on the evolutionary origins of corn.

  • Genetic Origin of Variation in Human Skin Color

    Genetic Origin of Variation in Human Skin Color

    Data Point

    Dr. Rebecca Lamason and colleagues studied the genetic origin of variation in human skin color using a model organism, the zebrafish.

  • How Species Coexist

    How Species Coexist

    Lecture

    (27 min 25 sec) Large herbivores in the African savanna coexist by partitioning ecological niches by time, space, and diet.

  • Film Guide for Popped Secret: The Mysterious Origin of Corn

    Film Guide for Popped Secret: The Mysterious Origin of Corn

    Film Guide

    The following classroom-ready resources complement the film Popped Secret: The Mysterious Origin of Corn, which tells the story of how geneticists and archaeologists have come together to determine how and where corn was domesticated nearly 9,000 years ago. Also available in Spanish.

  • Film Guide for The Biology of Skin Color

    Film Guide for The Biology of Skin Color

    Film Guide

    The following classroom-ready resources complement The Biology of Skin Color. Featuring anthropologist Dr. Nina Jablonski, the film walks us through the evidence that differences in human skin color are adaptations to varying intensity of UV light. Also available in Spanish.

  • Lactase Persistence: Evidence for Selection

    Lactase Persistence: Evidence for Selection

    Activity

    This activity provides a case study in human evolution that connects genotype, phenotype, culture, and graphical analysis skills. Also available in Spanish.

  • Genetics

    Genetics

    Collection

    BioInteractive offers many great resources for teaching genetics, including short films, animations, Click & Learn interactives, and classroom activities.

  • The Making of the Fittest

    The Making of the Fittest

    Collection

    Each film takes students on an adventure—from the postglacial lakes in southern Alaska to the deserts of the American Southwest, and from the icy Antarctic to the highlands of East Africa, where...

  • How We Get Our Skin Color

    How We Get Our Skin Color

    Animation

    (3 min 32 sec) This engaging animation shows how human skin cells produce the pigment melanin, which gives skin its color. 

  • The Biology of Skin Color

    The Biology of Skin Color

    Short Film

    (18 min 58 sec) Penn State University anthropologist Dr. Nina Jablonski walks us through the evidence that the different shades of skin color among human populations arose as adaptations to the intensity of ultraviolet radiation in different parts of the world. Also available in Spanish.

  • Icefish Film with Quiz

    Icefish Film with Quiz

    Interactive Video

    (13 min 14 sec) Embedded quiz modules test students’ understanding as they watch the short film on the icefish—an example of how genes are reused and recycled.

  • Ocean Species Respond to Climate Change

    Ocean Species Respond to Climate Change

    Lecture

    (29 min 39 sec) Coral reefs, how they are threatened by climate change, and how to protect them.

  • Rescuing Species

    Rescuing Species

    Lecture

    (29 min 1 sec) How to preserve genetic diversity that is threatened by habitat loss.

  • Popped Secret: The Mysterious Origin of Corn

    Popped Secret: The Mysterious Origin of Corn

    Short Film

    (17 min 51 sec) Where did corn come from? Genetic and archeological data point to what may seem like an unlikely ancestor: a wild Mexican grass called teosinte. Also available in Spanish.

  • Seeing Single Molecules Move

    Seeing Single Molecules Move

    Animation

    (1 min 40 sec) Single-molecule analysis using super-resolution microscopes reveals that transcription factors are not usually found bound to their binding sites on DNA.

  • The Eukaryotic Cell Cycle and Cancer

    The Eukaryotic Cell Cycle and Cancer

    Click & Learn

    Explore the phases, checkpoints, and protein regulators of the cell cycle in this highly interactive Click and Learn and find out how mutated versions of these proteins can lead to the development of cancer. Also available in Spanish.

  • Stickleback Evolution Virtual Lab App

    Stickleback Evolution Virtual Lab App

    Apps and eBooks

    App version of the popular virtual lab, introducing you to the science and techniques used to analyze the threespine stickleback fish.

  • Pedigrees and the Inheritance of Lactose Intolerance

    Pedigrees and the Inheritance of Lactose Intolerance

    Activity

    Students explore the genetic changes associated with lactose tolerance/intolerance and how the trait is inherited in families. Also available in Spanish.

  • Holiday Lecture 2004 Update—Jeff Friedman

    Holiday Lecture 2004 Update—Jeff Friedman

    Clip

    (3 min 52 sec) HHMI investigator Jeff Friedman provides an update to his 2004 lectures on obesity.

  • Mapping Genes to Traits in Dogs Using SNPs

    Mapping Genes to Traits in Dogs Using SNPs

    Activity

    In this hands-on genetic mapping activity students identify single nucleotide polymorphisms (SNPs) correlated with different traits in dogs.

  • Cancer Discovery Activities

    Cancer Discovery Activities

    Activity

    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video featuring researcher Dr. Charles L. Sawyers. Also available in Spanish.

  • Cancer as a Genetic Disease: Video Highlights

    Cancer as a Genetic Disease: Video Highlights

    Clip

    (8 min 32 sec) In this video Dr. Charles Sawyers provides an overview of the types of genes that, when mutated, can lead to the development of cancer. Also available in Spanish.

  • DNA

    DNA

    Collection

    From animations showing the details of DNA replication and transcription, to lecture segments that discuss DNA sequencing and PCR, and online interactives showing what sequence information reveals...

  • Pulse Chase Primer: The Meselson-Stahl Experiment

    Pulse Chase Primer: The Meselson-Stahl Experiment

    Activity

    This activity can be used in conjunction with the short film The Double Helix. It introduces students to the classic experiment by Matthew Meselson and Franklin Stahl, which revealed that DNA replication follows the semiconservative model.

  • Dante's Story

    Dante's Story

    Clip

    (6 min 6 sec) Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.

  • DNA Sequence Technology Improves Cancer Treatment

    DNA Sequence Technology Improves Cancer Treatment

    Clip

    (2 min 6 sec) Dr. Charles Sawyers discusses how the identification of most cancer genes could transform cancer into a chronic disease.

  • The Search for Genetic Mutations that Cause Autism

    The Search for Genetic Mutations that Cause Autism

    Clip

    (2 min 5 sec) Dr. Christopher Walsh discusses how genomic science has made enormous contributions to our understanding of the genetic causes of autism.

  • Meet Dante—A Young Boy with Hemimegalencephaly

    Meet Dante—A Young Boy with Hemimegalencephaly

    Clip

    (2 min 33 sec) Dante is a healthy 10-year-old boy who has had half his cerebral cortex surgically removed to treat his seizures.

  • Autism and the Structure and Function of Synapses

    Autism and the Structure and Function of Synapses

    Animation

    (2 min 3 sec) Genes associated with autism affect the structure and function of neuronal synapses.

  • Using DNA to Explore Lizard Phylogeny

    Using DNA to Explore Lizard Phylogeny

    Activity

    This activity supports the film The Origin of Species: Lizards in an Evolutionary Tree. Students are guided to sort the lizard species by appearance, then generate a phylogenetic tree using the lizards’ DNA sequences to evaluate whether species that appear similar are closely related to each other.

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