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  • Pelvic Evolution in Sticklebacks

    Pelvic Evolution in Sticklebacks

    Data Point

    Scientists used SNP genotyping in populations of freshwater stickleback fish to determine the genetic mutations responsible for the impaired development of pelvises and spines.

  • Teacher Guides

    Teacher Guides

    Collection

    Designed by educators, BioInteractive’s teacher guides will help you select BioInteractive resources aligned to specific topics and standards, including the AP® Biology Curriculum Framework.

  • Using Genetic Evidence to Identify Ivory Poaching Hotspots

    Using Genetic Evidence to Identify Ivory Poaching Hotspots

    Data Point

    A team of scientists analyzed the DNA from seized ivory to determine where the ivory from poached elephants came from.

  • Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease

    Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease

    Data Point

    A team of scientists built a pedigree of a large extended family in Antioquia, Colombia, that has a high prevalence of early-onset familial Alzheimer’s disease due to a mutation in the PSEN1 gene. Worksheets also available in Spanish.

  • Identifying Autism Genes by Tracking Gene Mutations

    Identifying Autism Genes by Tracking Gene Mutations

    Data Point

    A team of scientists used homozygosity mapping to map SNPs on chromosome 3 in a family with an autistic son to identify a likely gene that caused the disorder.

  • The Teosinte Hypothesis

    The Teosinte Hypothesis

    Activity

    In this lesson, students work through the mathematics and concepts behind George Beadle’s claim that teosinte is the wild ancestor of maize. Also available in Spanish.

  • Genetic Origin of Variation in Human Skin Color

    Genetic Origin of Variation in Human Skin Color

    Data Point

    Dr. Rebecca Lamason and colleagues studied the genetic origin of variation in human skin color using a model organism, the zebrafish.

  • Mapping Genes to Traits in Dogs Using SNPs

    Mapping Genes to Traits in Dogs Using SNPs

    Activity

    In this hands-on genetic mapping activity students identify single nucleotide polymorphisms (SNPs) correlated with different traits in dogs.

  • Got Lactase? Blood Glucose Data Analysis

    Got Lactase? Blood Glucose Data Analysis

    Activity

    Students interpret the results of two different tests for lactase persistence.

  • Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics

    Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics

    Activity

    A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics. Also available in Spanish.

  • Population Genetics, Selection, and Evolution

    Population Genetics, Selection, and Evolution

    Activity

    A hands-on activity that uses simulations with beads to teach students about population genetics, the Hardy-Weinberg principle, and how natural selection alters the frequency distribution of heritable traits. Also available in Spanish.

  • How to Analyze DNA Microarray Data

    How to Analyze DNA Microarray Data

    Click & Learn

    DNA microarrays, or gene chips, are an important new technology for genomic research. Learn how researchers use computing to analyze and interpret the huge datasets generated by microarray experiments.

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