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  • Gleevec-Resistant Form of Kinase BCR-ABL

    Gleevec-Resistant Form of Kinase BCR-ABL

    Animations

    (2 min 14 sec) Mutations in the BCR-ABL gene can cause resistance to Gleevec, but another drug, dasatinib, can be used instead.

  • Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Animations

    (3 min 31 sec) The drug Gleevec binds to and inactivates BCR-ABL, a mutant kinase that causes chronic myeloid leukemia. 

  • Film Guides: The Double Helix

    Film Guides: The Double Helix

    Film Guides

    The following classroom-ready resources complement The Double Helix. This short film describes the evidence that led James Watson and Francis Crick to the discovery of the double-helical structure of DNA and how the structure immediately revealed how genetic information is stored and inherited.

  • Lactose Intolerance: Fact or Fiction

    Lactose Intolerance: Fact or Fiction

    Activities

    Students evaluate and discuss several statements about lactose intolerance and evolution before and after watching the film. Also available in Spanish.

  • The Double Helix

    The Double Helix

    Short Films

    (16 min 53 sec) The Double Helix is the story of the scientists and evidence involved in one of the most important scientific quests of the 20th century: the discovery of the structure of DNA. Also available in Spanish.

  • Got Lactase? Blood Glucose Data Analysis

    Got Lactase? Blood Glucose Data Analysis

    Activities

    Students interpret the results of two different tests for lactase persistence.

  • Geological History of Oxygen

    Geological History of Oxygen

    Click & Learn

    Explore the changes in oxygen levels throughout Earth’s history and discover their impact on life.

  • Teacher Guide: DNA

    Teacher Guide: DNA

    Resource Guides

    Topics include: DNA structure and function, DNA replication, damage to DNA and eukaryotic chromosomal structure.

  • The Day the Mesozoic Died

    The Day the Mesozoic Died

    Short Films

    (33 min 43 sec) The disappearance of the dinosaurs at the end of the Cretaceous period posed one of the greatest, long-standing scientific mysteries. This three-act film tells the story of the extraordinary detective work that solved it. Also available in Spanish.

  • Lactose Digestion in Infants

    Lactose Digestion in Infants

    Animations

    (53 sec) The lactase enzyme is produced in the small intestine of infants. It digests lactose by breaking it into glucose and galactose.

  • Calculating Iridium Fallout From an Asteroid Impact

    Calculating Iridium Fallout From an Asteroid Impact

    Activities

    A worksheet in which students calculate how much iridium was released, and eventually deposited all over the Earth, by the impact of the asteroid that caused the K-T extinction.

  • Distribution of Elements in Earth’s Crust

    Distribution of Elements in Earth’s Crust

    Activities

    A lesson in which students read a passage and answer questions about the information presented, testing their non-fiction reading comprehension.

  • Chemical Signatures of Asteroid Impacts

    Chemical Signatures of Asteroid Impacts

    Activities

    A lesson in which students analyze the chemical data that led researchers to conclude that the K-T boundary layer contained an extraordinary concentration of iridium. 

  • Winogradsky columns: Microbial ecology in the classroom

    Winogradsky columns: Microbial ecology in the classroom

    Activities

    An activity that recreates zones of microbial activity in a glass column. To accompany the lecture series Changing Planet: Past, Present, Future.

  • Diet and the Evolution of Salivary Amylase

    Diet and the Evolution of Salivary Amylase

    Activities

    Students explore the effects of different diets on the evolution of an enzyme that breaks down starch. Also available in Spanish.

  • How Do Fibers Form?

    How Do Fibers Form?

    Activities

    A hands-on activity in which students construct models of sickle-cell hemoglobin fibers inside red blood cells to illustrate how changes in the structure of a protein can affect cell shape. Students are then asked to relate these changes to disease symptoms. Also available in Spanish.

  • Ice Crystal Formation in Icefish and Non-Icefish Blood

    Ice Crystal Formation in Icefish and Non-Icefish Blood

    Activities

    A dramatic demonstration that simulates how tiny ice crystals would form and grow in the blood of most fish if they ventured into the icy waters of the Antarctic.

  • Natural Selection and Evolution of Rock Pocket Mouse Populations

    Natural Selection and Evolution of Rock Pocket Mouse Populations

    Activities

    An activity in which students analyze amino acid data and draw conclusions about the evolution of coat color phenotypes in different rock pocket mouse populations.

  • Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Activities

    An advanced lesson that requires students to analyze partial DNA sequences of the Mc1r gene and identify the effects of mutations on the MC1R protein pathway.

  • Structure of Dengue Virus

    Structure of Dengue Virus

    Animations

    (1 min 3 sec) The dengue virus's outer envelope proteins form symmetrical units and overlay the lipid envelope, capsid, and the RNA genome.

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