Search Results

Search Results

Showing 1-40 of 78 Resources
  • Cystic Fibrosis Mechanism and Treatment

    Cystic Fibrosis Mechanism and Treatment

    Animation

    (2 min 31 sec) Mutations in the CFTR gene, which encodes a transmembrane ion channel, cause mucus buildup in the airways of patients with cystic fibrosis.

  • EarthViewer

    EarthViewer

    Click & Learn

    Download the accompanying student worksheet under "Downloads." What did Earth look like 250 million years ago? Or 1 billion years ago? Or 4.5 billion years ago? EarthViewer is an interactive tool that allows you to explore the science of Earth's deep history.

  • HIV Protease Inhibitors

    HIV Protease Inhibitors

    Activity

    This demonstration models how the HIV protease enzyme functions and how its activity is blocked by a class of anti-HIV drugs.

  • HIV Life Cycle Activities

    HIV Life Cycle Activities

    Collection

    A collection of activities and demonstrations focusing on various aspects of the human immunodeficiency virus (HIV) life cycle. They are designed to be completed individually or as part of the series...

  • Viral DNA Integration

    Viral DNA Integration

    Activity

    In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

  • HIV Reverse Transcription and AZT

    HIV Reverse Transcription and AZT

    Activity

    Students model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

  • HIV Receptors and Co-receptors

    HIV Receptors and Co-receptors

    Activity

    This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

  • Ocean Acidification

    Ocean Acidification

    Activity

    In this hands-on activity, students simulate the effects of decreasing pH caused by rising levels of atmospheric carbon dioxide.

  • Efficacy of a Treatment for Chronic Myeloid Leukemia

    Efficacy of a Treatment for Chronic Myeloid Leukemia

    Data Point

    Dr. Brian Druker and colleagues monitored white blood cell counts in six patients with chronic myeloid leukemia treated with the drug, STI571, which blocks the activity of the cancer-causing tyrosine kinase BCR-ABL.

  • How We Get Our Skin Color Interactive

    How We Get Our Skin Color Interactive

    Interactive Video

    (3 min 32 sec) This interactive animation about the biology of skin color provides stop points at which students can further explore the material through additional text and illustrations, videos, questions, and simple interactive widgets.

  • Chemistry of Life

    Chemistry of Life

    Collection

    Resources related to chemistry, biochemistry, and biological macromolecules such as DNA, RNA, proteins, carbohydrates, and lipids.

  • Seeing Single Molecules Move

    Seeing Single Molecules Move

    Animation

    (1 min 40 sec) Single-molecule analysis using super-resolution microscopes reveals that transcription factors are not usually found bound to their binding sites on DNA.

  • BCR-ABL: Cancer Protein Structure and Function

    BCR-ABL: Cancer Protein Structure and Function

    Click & Learn

    This Click and Learn describes how understanding the structure of the BCR-ABL kinase led to the development of an effective treatment for chronic myeloid leukemia.

  • Dasatinib

    Dasatinib

    3D Model

    A 3D model of dasatinib, a drug that can inhibit BCR-ABL and Gleevec-resistant BCR-ABL.


  • Imatinib (Gleevec)

    Imatinib (Gleevec)

    3D Model

    A 3D model of imatinib (Gleevec), a drug that mimics ATP and inhibits BCR-ABL.

  • Adenosine Triphosphate (ATP)

    Adenosine Triphosphate (ATP)

    3D Model

    A 3D model of adenosine triphosphate, or ATP.

  • Gleevec-resistant BCR-ABL: ABL Kinase Domain

    Gleevec-resistant BCR-ABL: ABL Kinase Domain

    3D Model

    A 3D model of gleevec-resistant BCR-ABL, a mutated form of BCR-ABL.

  • BCR-ABL: ABL Kinase Domain

    BCR-ABL: ABL Kinase Domain

    3D Model

    A 3D model of BCR-ABL, an unregulated kinase that causes cancer.

  • Earth Systems Activity

    Earth Systems Activity

    Activity

    This activity guides students through building a conceptual model of how carbon dioxide affects Earth's climate

  • Cancer As a Genetic Disease

    Cancer As a Genetic Disease

    Lecture

    (58 min 33 sec) Understanding that cancer is caused by mutations in genes that regulate cell proliferation has led to the development of targeted drug therapies.

  • Gleevec-Resistant Form of Kinase BCR-ABL

    Gleevec-Resistant Form of Kinase BCR-ABL

    Animation

    (2 min 14 sec) Mutations in the BCR-ABL gene can cause resistance to Gleevec, but another drug, dasatinib, can be used instead.

  • Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Animation

    (3 min 31 sec) The drug Gleevec binds to and inactivates BCR-ABL, a mutant kinase that causes chronic myeloid leukemia. 

  • Film Guides: The Double Helix

    Film Guides: The Double Helix

    Film Guide

    The following classroom-ready resources complement The Double Helix. This short film describes the evidence that led James Watson and Francis Crick to the discovery of the double-helical structure of DNA and how the structure immediately revealed how genetic information is stored and inherited.

  • Lactose Intolerance: Fact or Fiction

    Lactose Intolerance: Fact or Fiction

    Activity

    Students evaluate and discuss several statements about lactose intolerance and evolution before and after watching the film. Also available in Spanish.

  • The Double Helix

    The Double Helix

    Short Film

    (16 min 53 sec) The Double Helix is the story of the scientists and evidence involved in one of the most important scientific quests of the 20th century: the discovery of the structure of DNA. Also available in Spanish.

  • Got Lactase? Blood Glucose Data Analysis

    Got Lactase? Blood Glucose Data Analysis

    Activity

    Students interpret the results of two different tests for lactase persistence.

  • Geological History of Oxygen

    Geological History of Oxygen

    Click & Learn

    Explore the changes in oxygen levels throughout Earth’s history and discover their impact on life.

  • Teacher Guide: DNA

    Teacher Guide: DNA

    Teacher Guide

    Topics include: DNA structure and function, DNA replication, damage to DNA and eukaryotic chromosomal structure.

  • The Day the Mesozoic Died

    The Day the Mesozoic Died

    Short Film

    (33 min 43 sec) The disappearance of the dinosaurs at the end of the Cretaceous period posed one of the greatest, long-standing scientific mysteries. This three-act film tells the story of the extraordinary detective work that solved it. Also available in Spanish.

  • Earth's Climate: Back to the Future

    Earth's Climate: Back to the Future

    Lecture

    (1 hr 27 min 59 sec) Earth has been both cooler and warmer in the past, but the change is usually gradual. The current rate of carbon dioxide increase is unprecedented in human history, and solutions to mitigate its effect on global warming are challenging to implement.

  • Lactose Digestion in Infants

    Lactose Digestion in Infants

    Animation

    (53 sec) The lactase enzyme is produced in the small intestine of infants. It digests lactose by breaking it into glucose and galactose.

  • Calculating Iridium Fallout From an Asteroid Impact

    Calculating Iridium Fallout From an Asteroid Impact

    Activity

    A worksheet in which students calculate how much iridium was released, and eventually deposited all over the Earth, by the impact of the asteroid that caused the K-T extinction.

  • Distribution of Elements in Earth’s Crust

    Distribution of Elements in Earth’s Crust

    Activity

    A lesson in which students read a passage and answer questions about the information presented, testing their non-fiction reading comprehension.

  • Chemical Signatures of Asteroid Impacts

    Chemical Signatures of Asteroid Impacts

    Activity

    A lesson in which students analyze the chemical data that led researchers to conclude that the K-T boundary layer contained an extraordinary concentration of iridium. 

  • Winogradsky columns: Microbial ecology in the classroom

    Winogradsky columns: Microbial ecology in the classroom

    Activity

    An activity that recreates zones of microbial activity in a glass column. To accompany the lecture series Changing Planet: Past, Present, Future.

  • Diet and the Evolution of Salivary Amylase

    Diet and the Evolution of Salivary Amylase

    Activity

    Students explore the effects of different diets on the evolution of an enzyme that breaks down starch.

  • How Do Fibers Form?

    How Do Fibers Form?

    Activity

    A hands-on activity in which students construct models of sickle-cell hemoglobin fibers inside red blood cells to illustrate how changes in the structure of a protein can affect cell shape. Students are then asked to relate these changes to disease symptoms. Also available in Spanish.

  • Ice Crystal Formation in Icefish and Non-Icefish Blood

    Ice Crystal Formation in Icefish and Non-Icefish Blood

    Activity

    A dramatic demonstration that simulates how tiny ice crystals would form and grow in the blood of most fish if they ventured into the icy waters of the Antarctic.

  • Natural Selection and Evolution of Rock Pocket Mouse Populations

    Natural Selection and Evolution of Rock Pocket Mouse Populations

    Activity

    An activity in which students analyze amino acid data and draw conclusions about the evolution of coat color phenotypes in different rock pocket mouse populations.

  • Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Activity

    An advanced lesson that requires students to analyze partial DNA sequences of the Mc1r gene and identify the effects of mutations on the MC1R protein pathway.

Refine Results

Narrow your choices by selecting areas below.

Topics

Extended Filters