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Showing 1-21 of 21 Resources
  • Pelvic Evolution in Sticklebacks

    Pelvic Evolution in Sticklebacks

    Data Point

    Scientists used SNP genotyping in populations of freshwater stickleback fish to determine the genetic mutations responsible for the impaired development of pelvises and spines.

  • Stickleback Film with Quiz

    Stickleback Film with Quiz

    Interactive Video

    (15 min 27 sec) Embedded quiz modules test students’ understanding as they watch a short film that explains how stickleback fish let scientists study evolution in action, identify key genes, and peer deep into the evolutionary past.

  • The Making of the Fittest

    The Making of the Fittest

    Collection

    Each film takes students on an adventure—from the postglacial lakes in southern Alaska to the deserts of the American Southwest, and from the icy Antarctic to the highlands of East Africa, where...

  • Icefish Film with Quiz

    Icefish Film with Quiz

    Interactive Video

    (13 min 14 sec) Embedded quiz modules test students’ understanding as they watch the short film on the icefish—an example of how genes are reused and recycled.

  • Stickleback Evolution Virtual Lab App

    Stickleback Evolution Virtual Lab App

    Apps and eBooks

    App version of the popular virtual lab, introducing you to the science and techniques used to analyze the threespine stickleback fish.

  • Lactose Intolerance: Fact or Fiction

    Lactose Intolerance: Fact or Fiction

    Activity

    Students evaluate and discuss several statements about lactose intolerance and evolution before and after watching the film. Also available in Spanish.

  • Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

    Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

    Activity

    A hands-on activity in which students interpret molecular diagrams and build physical models of eukaryotic gene regulation.

  • Film Guides: Evolving Switches, Evolving Bodies

    Film Guides: Evolving Switches, Evolving Bodies

    Film Guide

    These classroom-ready resources complement the short film Evolving Switches, Evolving Bodies, which tells the story of the dramatic transformation of stickleback fish as they adapted to living in freshwater habitats drastically different from the ocean.

  • Teacher Guide: AP Biology

    Teacher Guide: AP Biology

    Teacher Guide

    This guide correlates all the resources available on the Holiday Lectures on Science DVDs and throughout the BioInteractive.org website to specific Big Ideas, Enduring Understandings, and Essential Knowledge threads of the new AP® Biology Curriculum Framework. 

  • The Making of the Fittest: Evolving Switches, Evolving Bodies

    The Making of the Fittest: Evolving Switches, Evolving Bodies

    Short Film

    (15 min 27 sec) After the end of the last ice age 10,000 years ago, populations of marine stickleback fish became stranded in freshwater lakes dotted throughout the Northern Hemisphere in places like Alaska and British Columbia. These fish have adapted to a freshwater environment drastically different than the ocean.

  • The Making of the Fittest: The Birth and Death of Genes

    The Making of the Fittest: The Birth and Death of Genes

    Short Film

    (13 min 10 sec) Scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as both the gain and loss of genes have led to key adaptations.

  • The Making of the Fittest: Natural Selection and Adaptation

    The Making of the Fittest: Natural Selection and Adaptation

    Short Film

    (10 min 25 sec) The rock pocket mouse is a living example of Darwin’s process of natural selection. Also available in Spanish.

  • The Molecular Evolution of Gene Birth and Death

    The Molecular Evolution of Gene Birth and Death

    Activity

    An advanced lesson that describes the role of mutations in the birth and death of genes. It includes background information, examples, video clips, and animations.

  • Film Guides: The Birth and Death of Genes

    Film Guides: The Birth and Death of Genes

    Film Guide

    The following classroom-ready resources complement The Making of the Fittest: The Birth and Death of Genes, which describes how scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as both the gain and loss of genes have led to key adaptations.

  • Molecular Genetics of Color Mutations in Rock Pocket Mice

    Molecular Genetics of Color Mutations in Rock Pocket Mice

    Activity

    A lesson that requires students to transcribe and translate portions of the wild-type and mutant rock pocket mouse Mc1r genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation described in the film. Also available in Spanish.

  • Genetic Switches

    Genetic Switches

    Click & Learn

    Learn about how gene switches can control expression of genes in different tissues.

  • Evolution: Constant Change and Common Threads

    Evolution: Constant Change and Common Threads

    Lecture

    How has the amazing diversity of plants and animals evolved? What can fossils, butterflies, and stickleback fish tell us about the deep common ancestry of all living forms?

  • Paintbrush Gene

    Paintbrush Gene

    Animation

    (49 sec) In two related Drosophila species, a so-called paintbrush gene is activated to "paint" the pigment on the body. In one species, an extra switch activates the gene, resulting in spotted wings.

  • Pitx1 Expression

    Pitx1 Expression

    Animation

    (55 sec) In the stickleback fish, pelvic-fin reduction resulted from changes in the regulatory switch elements of the Pitx1 gene. In the marine ancestor, the Pitx1 gene is activated in the pelvic-fin region during development to generate the fin. In the pelvic-reduced stickleback, the regulatory switch that normally turns on the Pitx1 gene is either missing or non-functional.

  • The Meaning of Sex: Genes and Gender

    The Meaning of Sex: Genes and Gender

    Lecture

    Four talks focus on sex determination—the molecular and genetic mechanisms that determine whether an organism will be male, female or a hermaphrodite.

  • The Y Chromosome

    The Y Chromosome

    Animation

    (2 min 46 sec) The Y chromosome has been likened to a hall of mirrors because its sequence contains many sections that appear to be palindromes. These palindromes provide a clue to some interesting events that may have occurred during the course of the chromosome's evolution.

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