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Data PointsResearchers investigated the role of p53 in cell cycle regulation by genetically engineering cell lines with disrupted alleles of the p53 gene. They exposed the cell lines to DNA-damaging radiation and observed how this exposure impacted mitosis.
Data PointsCancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. In this study, researchers investigated how a third factor—chance genetic mutations that occur during stem cell division—may contribute to the overall rate of cancer incidence in different body tissues.
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