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  • Resource Guides

    Resource Guides

    Collection

    Designed by educators, BioInteractive’s resource guides will help you select BioInteractive resources aligned to specific topics and standards, including the AP® Biology Curriculum Framework.

  • Lactase Film with Quiz

    Lactase Film with Quiz

    Interactive Videos

    (14 min 52 sec) Embedded quiz modules test students’ understanding as they watch a short film that explores the evolution of the ability to digest lactose as adults (lactose tolerance) and the genetic changes associated with the trait.

  • How We Get Our Skin Color

    How We Get Our Skin Color

    Animations

    (3 min 32 sec) This engaging animation shows how human skin cells produce the pigment melanin, which gives skin its color. 

  • Lactose Intolerance: Fact or Fiction

    Lactose Intolerance: Fact or Fiction

    Activities

    Students evaluate and discuss several statements about lactose intolerance and evolution before and after watching the film. Also available in Spanish.

  • Got Lactase? Blood Glucose Data Analysis

    Got Lactase? Blood Glucose Data Analysis

    Activities

    Students interpret the results of two different tests for lactase persistence.

  • Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

    Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

    Activities

    A hands-on activity in which students interpret molecular diagrams and build physical models of eukaryotic gene regulation.

  • The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture

    The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture

    Short Films

    (14 min 52 sec) Follow human geneticist Spencer Wells, Director of the Genographic Project of the National Geographic Society, as he tracks down the genetic changes associated with the ability to digest lactose as adults. Also available in Spanish.

  • Teacher Guide: AP Biology

    Teacher Guide: AP Biology

    Resource Guides

    This guide correlates all the resources available on the Holiday Lectures on Science DVDs and throughout the BioInteractive.org website to specific Big Ideas, Enduring Understandings, and Essential Knowledge threads of the new AP® Biology Curriculum Framework. 

  • Pitx1 Expression

    Pitx1 Expression

    Animations

    (55 sec) In the stickleback fish, pelvic-fin reduction resulted from changes in the regulatory switch elements of the Pitx1 gene. In the marine ancestor, the Pitx1 gene is activated in the pelvic-fin region during development to generate the fin. In the pelvic-reduced stickleback, the regulatory switch that normally turns on the Pitx1 gene is either missing or non-functional.

  • PPAR-gamma Activation in the Fat Cell

    PPAR-gamma Activation in the Fat Cell

    Animations

    (2 min 49 sec) The PPAR-gamma receptor activates certain genes in a fat cell, resulting in the storage of fat and changes in hormone levels.

  • X Inactivation

    X Inactivation

    Animations

    (55 sec) This animation shows how the random deactivation of one of the X chromosomes in a pair can lead to a mozaicism in the expression genes. 

  • The Drosophila Molecular Clock Model

    The Drosophila Molecular Clock Model

    Animations

    (7 min 35 sec) Watch these animations display the dynamic orchestration of the molecular events of the Drosophila biological clock.

  • The Mammalian Molecular Clock Model

    The Mammalian Molecular Clock Model

    Animations

    (3 min 41 sec) This animation shows the molecular interactions involved in the negative feedback loop responsible for circadian rhythms in mammals.

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