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Showing 1-20 of 77 Resources
  • Cystic Fibrosis Mechanism and Treatment

    Cystic Fibrosis Mechanism and Treatment

    Animations

    (2 min 31 sec) Mutations in the CFTR gene, which encodes a transmembrane ion channel, cause mucus buildup in the airways of patients with cystic fibrosis.

  • Solving Crimes with the NECROBIOME

    Solving Crimes with the NECROBIOME

    Feature Films

    (7 min 10 sec) We can’t talk to the dead, but in their own way, the dead can speak to us.

  • The Search for a Mutated Gene

    The Search for a Mutated Gene

    Scientists at Work

    (8 min 54 sec) How do you identify the disease-causing mutation in a patient with an inherited disease? This video illustrates the steps involved—testing for genes that are the “usual suspects,” searching for mutations in novel genes, and assessing links between genotype and phenotype.

  • Genes as Medicine

    Genes as Medicine

    Short Films

    (17 min 16 sec) Watch the story of how gene therapy restored the sight of a nearly-blind young patient. Told from the perspective of two researchers who spent over 25 years working to develop this breakthrough technology, this short film chronicles their successes and challenges, and illustrates how the method works to treat inherited conditions.

  • Think Like a Scientist: Natural Selection in an Outbreak

    Think Like a Scientist: Natural Selection in an Outbreak

    Scientists at Work

    (7 min 29 sec) This video brings us to the front lines of the 2013–2015 Ebola outbreak in west Africa and explains how scientists monitored the evolution of the virus by analyzing its genome.

  • Genetically Modified Mosquitoes

    Genetically Modified Mosquitoes

    Scientists at Work

    (8 min 35 sec) Learn the process by which a line of genetically modified mosquitoes was engineered to reduce populations of Aedes aegypti mosquitoes in the wild.

  • How We Get Our Skin Color

    How We Get Our Skin Color

    Animations

    (3 min 32 sec) This engaging animation shows how human skin cells produce the pigment melanin, which gives skin its color. 

  • The Biology of Skin Color

    The Biology of Skin Color

    Short Films

    (18 min 58 sec) Penn State University anthropologist Dr. Nina Jablonski walks us through the evidence that the different shades of skin color among human populations arose as adaptations to the intensity of ultraviolet radiation in different parts of the world. Also available in Spanish.

  • Popped Secret: The Mysterious Origin of Corn

    Popped Secret: The Mysterious Origin of Corn

    Short Films

    (17 min 51 sec) Where did corn come from? Genetic and archeological data point to what may seem like an unlikely ancestor: a wild Mexican grass called teosinte. Also available in Spanish.

  • Seeing Single Molecules Move

    Seeing Single Molecules Move

    Animations

    (1 min 40 sec) Single-molecule analysis using super-resolution microscopes reveals that transcription factors are not usually found bound to their binding sites on DNA.

  • Holiday Lecture 2004 Update—Jeff Friedman

    Holiday Lecture 2004 Update—Jeff Friedman

    Clips

    (3 min 52 sec) HHMI investigator Jeff Friedman provides an update to his 2004 lectures on obesity.

  • Cancer as a Genetic Disease: Video Highlights

    Cancer as a Genetic Disease: Video Highlights

    Clips

    (8 min 32 sec) In this video Dr. Charles Sawyers provides an overview of the types of genes that, when mutated, can lead to the development of cancer. Also available in Spanish.

  • Dante's Story

    Dante's Story

    Clips

    (6 min 6 sec) Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.

  • DNA Sequence Technology Improves Cancer Treatment

    DNA Sequence Technology Improves Cancer Treatment

    Clips

    (2 min 6 sec) Dr. Charles Sawyers discusses how the identification of most cancer genes could transform cancer into a chronic disease.

  • The Search for Genetic Mutations that Cause Autism

    The Search for Genetic Mutations that Cause Autism

    Clips

    (2 min 5 sec) Dr. Christopher Walsh discusses how genomic science has made enormous contributions to our understanding of the genetic causes of autism.

  • Meet Dante—A Young Boy with Hemimegalencephaly

    Meet Dante—A Young Boy with Hemimegalencephaly

    Clips

    (2 min 33 sec) Dante is a healthy 10-year-old boy who has had half his cerebral cortex surgically removed to treat his seizures.

  • Autism and the Structure and Function of Synapses

    Autism and the Structure and Function of Synapses

    Animations

    (2 min 3 sec) Genes associated with autism affect the structure and function of neuronal synapses.

  • Gleevec-Resistant Form of Kinase BCR-ABL

    Gleevec-Resistant Form of Kinase BCR-ABL

    Animations

    (2 min 14 sec) Mutations in the BCR-ABL gene can cause resistance to Gleevec, but another drug, dasatinib, can be used instead.

  • Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Animations

    (3 min 31 sec) The drug Gleevec binds to and inactivates BCR-ABL, a mutant kinase that causes chronic myeloid leukemia. 

  • The Double Helix

    The Double Helix

    Short Films

    (16 min 53 sec) The Double Helix is the story of the scientists and evidence involved in one of the most important scientific quests of the 20th century: the discovery of the structure of DNA. Also available in Spanish.

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