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Showing 1-20 of 26 Resources
  • Developing an Explanation for Mouse Fur Color

    Developing an Explanation for Mouse Fur Color

    Activity

    Students collect and analyze evidence for each of the major conditions for evolution by natural selection to develop an explanation for how populations change over time. Also available in Spanish.

  • Central Dogma Card Activity

    Central Dogma Card Activity

    Activity

    In this hands-on activity students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat genetic disease.

  • Stalking the Genetic Basis of a Trait

    Stalking the Genetic Basis of a Trait

    Activity

    In this activity students analyze data on the expression of the tb1 gene and use it to formulate an explanation as to how a specific difference in the corn version of the gene explains the phenotype of less branching.

  • Patterns in the Distribution of Lactase Persistence

    Patterns in the Distribution of Lactase Persistence

    Activity

    Students explore the geographic distribution of lactase persistence around the world by analyzing real data collected by scientists.

  • DNA Profiling Activity

    DNA Profiling Activity

    Activity

    This multi-part lesson is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world. 

  • Understanding Variation

    Understanding Variation

    Activity

    This lesson complements the film The Biology of Skin Color and discusses variation in human skin color and polygenic inheritance. Also available in Spanish.

  • Zebrafish and Skin Color

    Zebrafish and Skin Color

    Activity

    This lesson complements the film The Biology of Skin Color and explores how experimental work in zebrafish led to a better understanding of the role of the gene SLC24A5 in human skin color.

  • The Teosinte Hypothesis

    The Teosinte Hypothesis

    Activity

    In this lesson, students work through the mathematics and concepts behind George Beadle’s claim that teosinte is the wild ancestor of maize. Also available in Spanish.

  • Lactase Persistence: Evidence for Selection

    Lactase Persistence: Evidence for Selection

    Activity

    This activity provides a case study in human evolution that connects genotype, phenotype, culture, and graphical analysis skills. Also available in Spanish.

  • Pedigrees and the Inheritance of Lactose Intolerance

    Pedigrees and the Inheritance of Lactose Intolerance

    Activity

    Students explore the genetic changes associated with lactose tolerance/intolerance and how the trait is inherited in families. Also available in Spanish.

  • Mapping Genes to Traits in Dogs Using SNPs

    Mapping Genes to Traits in Dogs Using SNPs

    Activity

    In this hands-on genetic mapping activity students identify single nucleotide polymorphisms (SNPs) correlated with different traits in dogs.

  • Cancer Discovery Activities

    Cancer Discovery Activities

    Activity

    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video featuring researcher Dr. Charles L. Sawyers. Also available in Spanish.

  • Pulse Chase Primer: The Meselson-Stahl Experiment

    Pulse Chase Primer: The Meselson-Stahl Experiment

    Activity

    This activity can be used in conjunction with the short film The Double Helix. It introduces students to the classic experiment by Matthew Meselson and Franklin Stahl, which revealed that DNA replication follows the semiconservative model.

  • Using DNA to Explore Lizard Phylogeny

    Using DNA to Explore Lizard Phylogeny

    Activity

    This activity supports the film The Origin of Species: Lizards in an Evolutionary Tree. Students are guided to sort the lizard species by appearance, then generate a phylogenetic tree using the lizards’ DNA sequences to evaluate whether species that appear similar are closely related to each other.

  • Lactose Intolerance: Fact or Fiction

    Lactose Intolerance: Fact or Fiction

    Activity

    Students evaluate and discuss several statements about lactose intolerance and evolution before and after watching the film. Also available in Spanish.

  • Got Lactase? Blood Glucose Data Analysis

    Got Lactase? Blood Glucose Data Analysis

    Activity

    Students interpret the results of two different tests for lactase persistence.

  • Using Genetic Crosses to Analyze a Stickleback Trait

    Using Genetic Crosses to Analyze a Stickleback Trait

    Activity

    A hands-on activity in which students analyze the results of genetic crosses between stickleback fish with different traits.

  • Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

    Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

    Activity

    A hands-on activity in which students interpret molecular diagrams and build physical models of eukaryotic gene regulation.

  • Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics

    Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics

    Activity

    A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics. Also available in Spanish.

  • Testing a Hypothesis

    Testing a Hypothesis

    Activity

    A worksheet designed to actively engage students as they watch the film. Students are asked to answer questions pertaining to the information provided in the film.

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