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Showing 1-20 of 36 Resources
  • Cystic Fibrosis Mechanism and Treatment

    Cystic Fibrosis Mechanism and Treatment

    Animation

    (2 min 31 sec) Mutations in the CFTR gene, which encodes a transmembrane ion channel, cause mucus buildup in the airways of patients with cystic fibrosis.

  • CRISPR-Cas 9 Mechanism & Applications

    CRISPR-Cas 9 Mechanism & Applications

    Click & Learn

    Explore this dynamic interactive to learn the basic principles of how this revolutionary tool works and the many ways in which scientists are using it in their research.

  • Central Dogma Card Activity

    Central Dogma Card Activity

    Activity

    In this hands-on activity students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat genetic disease.

  • Film Guide for Genes as Medicine

    Film Guide for Genes as Medicine

    Film Guide

    The following classroom-ready resources complement the film Genes as Medicine. It tells the story of the successes and challenges that led to the development of the first FDA-approved gene therapy for a genetic disease.

  • The Search for a Mutated Gene

    The Search for a Mutated Gene

    Scientists at Work

    (8 min 54 sec) How do you identify the disease-causing mutation in a patient with an inherited disease? This video illustrates the steps involved—testing for genes that are the “usual suspects,” searching for mutations in novel genes, and assessing links between genotype and phenotype.

  • Genes as Medicine

    Genes as Medicine

    Short Film

    (17 min 16 sec) Watch the story of how gene therapy restored the sight of a nearly-blind young patient. Told from the perspective of two researchers who spent over 25 years working to develop this breakthrough technology, this short film chronicles their successes and challenges, and illustrates how the method works to treat inherited conditions.

  • Central Dogma and Genetic Medicine

    Central Dogma and Genetic Medicine

    Click & Learn

    This interactive uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat genetic diseases.

  • Teacher Guides

    Teacher Guides

    Collection

    Designed by educators, BioInteractive’s teacher guides will help you select BioInteractive resources aligned to specific topics and standards, including the AP® Biology Curriculum Framework.

  • DNA Profiling Activity

    DNA Profiling Activity

    Activity

    This multi-part lesson is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world. 

  • Genetically Modified Mosquitoes

    Genetically Modified Mosquitoes

    Scientists at Work

    (8 min 35 sec) Learn the process by which a line of genetically modified mosquitoes was engineered to reduce populations of Aedes aegypti mosquitoes in the wild.

  • CSI Wildlife

    CSI Wildlife

    Click & Learn

    In this interactive, students use DNA profiling, or fingerprinting, to solve two cases of elephant poaching. In the process they will learn about genetic markers, PCR, gel electrophoresis, allele frequencies, and population genetics.

  • Seeing Single Molecules Move

    Seeing Single Molecules Move

    Animation

    (1 min 40 sec) Single-molecule analysis using super-resolution microscopes reveals that transcription factors are not usually found bound to their binding sites on DNA.

  • DNA Sequence Technology Improves Cancer Treatment

    DNA Sequence Technology Improves Cancer Treatment

    Clip

    (2 min 6 sec) Dr. Charles Sawyers discusses how the identification of most cancer genes could transform cancer into a chronic disease.

  • Film Guides: The Double Helix

    Film Guides: The Double Helix

    Film Guide

    The following classroom-ready resources complement The Double Helix. This short film describes the evidence that led James Watson and Francis Crick to the discovery of the double-helical structure of DNA and how the structure immediately revealed how genetic information is stored and inherited.

  • Teacher Guide: Biotechnology

    Teacher Guide: Biotechnology

    Teacher Guide

    Topics include: PCR, DNA Sequencing, Genetic Engineering, and Microarray. This guide includes multiple classroom-ready worksheets to accompany HHMI’s virtual labs.

  • Teacher Guide: AP Biology

    Teacher Guide: AP Biology

    Teacher Guide

    This guide correlates all the resources available on the Holiday Lectures on Science DVDs and throughout the BioInteractive.org website to specific Big Ideas, Enduring Understandings, and Essential Knowledge threads of the new AP® Biology Curriculum Framework. 

  • Bacterial ID Virtual Lab App

    Bacterial ID Virtual Lab App

    Apps and eBooks

    Learn about the science and techniques used to identify different types of bacteria based on their DNA sequences

  • Virochip DNA Microarray

    Virochip DNA Microarray

    Click & Learn

    Answer interactive questions to explore the logic of the Virochip microarray design, particularly how evolutionary relationships can be used to detect new viruses.

  • DNA Sequence Assembly

    DNA Sequence Assembly

    Click & Learn

    Learn the principles of how DNA is sequenced and assembled into whole genomes using the Sanger method, shotgun sequencing, or ultra-deep sequencing.

  • Solving SARS and Other Viral Mysteries

    Solving SARS and Other Viral Mysteries

    Lecture

    (58 min 33 sec) The SARS epidemic was successfully halted by a global research effort to identify a new virus.

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