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Showing 1-20 of 25 Resources
  • Cystic Fibrosis Mechanism and Treatment

    Cystic Fibrosis Mechanism and Treatment

    Animations

    (2 min 31 sec) Mutations in the CFTR gene, which encodes a transmembrane ion channel, cause mucus buildup in the airways of patients with cystic fibrosis.

  • HIV Protease Inhibitors

    HIV Protease Inhibitors

    Activities

    This demonstration models how the HIV protease enzyme functions and how its activity is blocked by a class of anti-HIV drugs.

  • Viral DNA Integration

    Viral DNA Integration

    Activities

    In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

  • HIV Reverse Transcription and AZT

    HIV Reverse Transcription and AZT

    Activities

    Students model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

  • HIV Receptors and Co-receptors

    HIV Receptors and Co-receptors

    Activities

    This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

  • Ocean Acidification

    Ocean Acidification

    Activities

    In this hands-on activity, students simulate the effects of decreasing pH caused by rising levels of atmospheric carbon dioxide.

  • How We Get Our Skin Color Interactive

    How We Get Our Skin Color Interactive

    Interactive Videos

    (3 min 32 sec) This interactive animation about the biology of skin color provides stop points at which students can further explore the material through additional text and illustrations, videos, questions, and simple interactive widgets.

  • BCR-ABL: Cancer Protein Structure and Function

    BCR-ABL: Cancer Protein Structure and Function

    Click & Learn

    This Click and Learn describes how understanding the structure of the BCR-ABL kinase led to the development of an effective treatment for chronic myeloid leukemia.

  • Film Guides: The Double Helix

    Film Guides: The Double Helix

    Film Guides

    The following classroom-ready resources complement The Double Helix. This short film describes the evidence that led James Watson and Francis Crick to the discovery of the double-helical structure of DNA and how the structure immediately revealed how genetic information is stored and inherited.

  • Lactose Intolerance: Fact or Fiction

    Lactose Intolerance: Fact or Fiction

    Activities

    Students evaluate and discuss several statements about lactose intolerance and evolution before and after watching the film. Also available in Spanish.

  • Lactose Digestion in Infants

    Lactose Digestion in Infants

    Animations

    (53 sec) The lactase enzyme is produced in the small intestine of infants. It digests lactose by breaking it into glucose and galactose.

  • Diet and the Evolution of Salivary Amylase

    Diet and the Evolution of Salivary Amylase

    Activities

    Students explore the effects of different diets on the evolution of an enzyme that breaks down starch. Also available in Spanish.

  • How Do Fibers Form?

    How Do Fibers Form?

    Activities

    A hands-on activity in which students construct models of sickle-cell hemoglobin fibers inside red blood cells to illustrate how changes in the structure of a protein can affect cell shape. Students are then asked to relate these changes to disease symptoms. Also available in Spanish.

  • Ice Crystal Formation in Icefish and Non-Icefish Blood

    Ice Crystal Formation in Icefish and Non-Icefish Blood

    Activities

    A dramatic demonstration that simulates how tiny ice crystals would form and grow in the blood of most fish if they ventured into the icy waters of the Antarctic.

  • Natural Selection and Evolution of Rock Pocket Mouse Populations

    Natural Selection and Evolution of Rock Pocket Mouse Populations

    Activities

    An activity in which students analyze amino acid data and draw conclusions about the evolution of coat color phenotypes in different rock pocket mouse populations.

  • Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Activities

    An advanced lesson that requires students to analyze partial DNA sequences of the Mc1r gene and identify the effects of mutations on the MC1R protein pathway.

  • The Chemical Structure of DNA

    The Chemical Structure of DNA

    Animations

    (2 min 44 sec) DNA's chemical properties can be harnessed for a variety of biotechnology applications.

  • Signal molecules trigger transcription factors

    Signal molecules trigger transcription factors

    Animations

    (2 min 4 sec) Varying concentrations of a signaling molecule activate different transcription factors and determine cell fate.

  • Visualizing Gene-Expression Patterns

    Visualizing Gene-Expression Patterns

    Click & Learn

    Learn about the different ways scientists are able to detect when genes are being expressed in various tissues.

  • Triplet code

    Triplet code

    Animations

    (1 min 8 sec) Once the structure of DNA was discovered, the next challenge was determining how the sequence of letters coded for the 20 amino acids. In theory, one or two letters can only code for 4 or 16 amino acids, respectively. A scheme using three letters, a triplet code, is the minimum necessary to encode for all the amino acids.

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