Role of p53 in the Cell Cycle

Graph from the paper


Researchers investigated the role of p53 in cell cycle regulation by genetically engineering cell lines with disrupted alleles of the p53 gene. They exposed the cell lines to DNA-damaging radiation and observed how this exposure impacted mitosis.

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Curriculum Connections:

NGSS (2013)
AP Biology (2015)
3.A.2, SP5, SP6
IB Biology (2016)
Common Core (2010)
ELA.RST.9-12.7, Math.S-ID.3, S-ID.1, MP2, MP5
Vision and Change (2009)
CC5, DP2