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PPAR-gamma Activation in the Fat Cell

More About PPAR-gamma Activation in the Fat Cell

The PPAR-gamma receptor activates certain genes in a fat cell, resulting in the storage of fat and changes in hormone levels. 

PPAR-gamma Activation in the Fat Cell Background

PPAR-gamma is one of a family of receptors that is responsible for regulating the burning or storing of fat. Drugs can be designed to activate the PPAR-gamma receptor. Once activated, it in turn activates certain genes. The products of these genes cause the fat cell to store fat rather than release it into the body. This increase in stored fat also changes the levels of certain hormones released by the fat cell.

From Lecture Three of the 2004 Holiday Lectures Series "The Science of Fat."

PPAR-gamma Activation in the Fat Cell Teaching Tips

The animations in this section have a wide variety of classroom applications. Use the tips below to get started but look for more specific teaching tips in the near future. Please tell us how you are using the animations in your classroom by sending e-mail to biointeractive@hhmi.org.

  1. Use the animations to make abstract scientific ideas visible and concrete.
  2. Explain important scientific principles through the animations. For example, the biological clocks animations can be used to demonstrate the fundamentals of transcription and translation.
  3. Make sure that students learn the material by repeating sections of the animations as often as you think necessary to reinforce underlying scientific principles. You can start, restart, and play back sections of the animations.
  4. Urge students to use the animations in accordance with their own learning styles. Students who are more visually oriented can watch the animations first and read the text later, while others might prefer to read the explanations first and then view the graphics.
  5. Incorporate the animations into Web-based learning modules that you create to supplement your classroom curricula.
  6. Encourage students to incorporate the animations into their own Web-based projects.


The 2004 Holiday Lectures Series "The Science of Fat"

PPAR-gamma Activation in the Fat Cell Credits

Director: Dennis Liu, Ph.D.

Scientific Direction: Ronald Evans, Ph.D.

Scientific Content: Satoshi Amagai, Ph.D.

Animator: Eric Keller

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