Students explore the genetic changes associated with lactose tolerance/intolerance and how the trait is inherited in families.
In this classroom activity, students analyze the same Finnish family pedigrees that researchers studied to understand the pattern of inheritance of lactose tolerance/intolerance. They also examine portions of DNA sequence near the lactase gene to identify specific mutations associated with lactose tolerance. The activity is intended for regular and honors high school biology. Images from the activity are available in the linked PowerPoint (PPT) file.
NGSS (April 2013)
HS-LS3-1, HS-LS2.A, HS-LS3.A
Common Core (2010)
CCSS.ELA-Literacy.RST.9-10.3, CCSS.ELA-Literacy.RST.9-10.5, CCSS.ELA-Literacy.RST.9-10.7, CCSS.ELA-Literacy.RST.9-10.4, CCSS.ELA-Literacy.RST.11-12.4, CCSS.ELA-Literacy.RST.11-12.3, CCSS.ELA-Literacy.RH.9-10.4, CCSS.ELA-Literacy.RH.9-10.7, CCSS.ELA-Literacy.RH.11-12.4
AP Biology (2012-13)
3.A.3, 3.B.1, 3.C.1, 4.A.1, LO 3.14, LO 3.18, LO 3.19
IB Biology (2009)
3.3, 4.1, 4.3