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Eavesdropping on Tiny Conspiracies


The quorum sensing system is a target for a new class of drugs that interfere with virulence without killing bacteria.

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(Duration: 58 min 29 sec)

Pathogenic bacteria use quorum sensing to launch a simultaneous attack when in sufficient numbers. Bacteria possess at least two systems of quorum sensing. They sense their own species' numbers by monitoring their species-specific quorum sensing signal. Bacteria also sense a signal that is shared between different species to obtain information about the bacterial community. Manipulating quorum sensing is a promising approach for developing new antibiotics against pathogens, or probiotics for industrial applications.

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