Follow the leader? This image shows cells in a primary breast cancer tumor invading the surrounding muscle tissue (blue). Both the green and pink-stained cells are tumor cells, but the pink cells represent ‘leader’ cells – cells that break off from the main body of the green tumor and begin to metastasize, a process by which cancers from a primary tumor invade and colonize other tissues. These leader cells are both genetically and behaviorally different from the main body of the tumor. Researchers hope to identify the genetic mutations that cause cells to become ‘leaders’ to give them new opportunities for treating breast cancers and preventing metastasis.
The downloadable Educator Materials PDF includes background information and implementation suggestions for using the image as a phenomenon. The Student Handout includes the image and background.
Kevin Cheung, MD, Fred Hutchinson Cancer Research Center
Date Created 08/27/2018
Date Modified 08/27/2018
The documents for this resource have been remediated to comply with Section 508 of the National Rehabilitation Act for accessibility and can be used with screen readers.