Is it a boy or a girl? Dr. David Page looks at how we define male and female and summarizes the development of human sex characteristics.
Dr. Barbara Meyer explains the value of studying model organisms and introduces the nematode C. elegans.
Having too many chromosomes can lead to too much gene expression. Dr. Meyer explains how the gene that controls dosage compensation in C. elegans works.
Dr. Page explains how successive inversions and deletions of the Y chromosome during mammalian evolution have reduced it to its present form—small and sparsely populated with genes.