Varying concentrations of a signaling molecule activate different transcription factors and determine cell fate.
Electrical and chemical signals are used by neurons to communicate with one another at contact points called synapses.
Long-term memory requires the activation of CREB, turning on specific genes that support new synaptic growth.
Short-term memory relies on serotonin activating a protein kinase to modify existing synaptic strength.
Early LTP (short-term memory) depends on a calcium-dependent protein kinase to strengthen an existing synapse.
Late LTP (long-term memory) involves dopamine activation of CREB to support new synaptic growth.
How a nerve cell gets its identity, sends axons, and makes connections with other cells.
Understanding the neural circuits in the spinal cord that control movement.
The cellular and molecular nature of learning and memory, investigated in simpler sea slugs and more-complex mice.
The poster from the 2008 Holiday Lectures on Science, Making Your Mind: Molecules, Motion, and Memory. It illustrates the structure and function of a neuron, including how it transmits electrical and chemical signals.
(This poster is designed to printed at a maximum size of 29.5...
A growth cone contacts a repellant molecule on another axon, collapses, and withdraws.
A live recording of muscle activity from Dr. Jessell's biceps and triceps muscles.
A reduction in the level of sonic hedgehog (SHH) gene expression can lead to cyclopia.
Retinal axons travel across the brain, reading navigation cues, to find appropriate targets.
Dr. Harshad Vishwasrao guides you through a collection of images showing neuronal growth and synaptic formation representative of anatomical changes that occur during learning.