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HHMI - Howard Hughes Medical Institue

At the Howard Hughes Medical Institute, we believe in the power of individuals to advance science through research and science education, making discoveries that benefit humanity. Learn more about how we move science forward. Investigator Nikolaus Grigorieff »
Research Dec 10 2019
How to “Read” the Brain Signals Underlying Human Speech

Scientists have discovered that a brain region that controls hand and arm movement also offers a window into studying speech. The work brings researchers a step closer to building medical devices that help people who cannot speak.

Research Nov 20 2019
To Navigate, Flies Make Flexible Mental Maps of the World

Flies use visual cues to finesse their mental maps of the environment. Two new studies use virtual reality to show how. 

Research Nov 15 2019
Brain-Enhancing Drug Reverses Down Syndrome Memory Deficits in Mice

Activity goes awry for hundreds of genes in Down syndrome, the most common genetic cause of intellectual disability. Scientists have now found a way to calm the disordered activity – and restore cognitive abilities in mice.

Institute Oct 22 2019
HHMI Investigator Program Opens National Competition

HHMI is seeking to appoint approximately 20 new Investigators through a national open competition. This effort will expand HHMI’s community of nearly 300 Investigators, who perform basic biological research across the nation.

Institute Nov 01 2019
HHMI Announces Driving Change Initiative

HHMI's Driving Change initiative aims to effect genuine and lasting culture change on research university campuses so that undergraduate students from all backgrounds, particularly those who belong to historically excluded groups, will excel in STEM. Letters of intent due February 7, 2020.

Research Nov 14 2019
Here’s One Way Zika Virus Causes Microcephaly

The mosquito-borne virus can harm fetuses in utero and cause the brain condition microcephaly. Now, scientists have identified a genetic pathway that’s targeted by Zika and revealed one protein’s role in brain development.

Research Oct 31 2019
Measles Virus Infection Destroys Immune System Memory

In humans and macaques, measles infection wipes out antibodies to previous pathogens and could make individuals more susceptible to disease. Until now, such long-term consequences of measles had been unknown.

Research Oct 18 2019
Whole Genome Sequencing Could Help Save Pumas from Inbreeding

The first complete genetic sequences of individual mountain lions point the way to better conservation strategies for saving threatened populations of the wild animals.

Webcast Oct 14 2019
Research Assessment Reform Meeting, Oct 21-22

HHMI and the San Francisco Declaration on Research Assessment (DORA) are convening a diverse group of stakeholders from across academia to consider how to improve research assessment policies and practices. All are invited to livestream the keynote, panel, and plenary talk sessions.

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Research Dec 10 2019
How to “Read” the Brain Signals Underlying Human Speech

Scientists have discovered that a brain region that controls hand and arm movement also offers a window into studying speech. The work brings researchers a step closer to building medical devices that help people who cannot speak.

Research Nov 20 2019
To Navigate, Flies Make Flexible Mental Maps of the World

Flies use visual cues to finesse their mental maps of the environment. Two new studies use virtual reality to show how. 

Research Nov 15 2019
Brain-Enhancing Drug Reverses Down Syndrome Memory Deficits in Mice

Activity goes awry for hundreds of genes in Down syndrome, the most common genetic cause of intellectual disability. Scientists have now found a way to calm the disordered activity – and restore cognitive abilities in mice.

Institute Oct 22 2019
HHMI Investigator Program Opens National Competition

HHMI is seeking to appoint approximately 20 new Investigators through a national open competition. This effort will expand HHMI’s community of nearly 300 Investigators, who perform basic biological research across the nation.

Institute Nov 01 2019
HHMI Announces Driving Change Initiative

HHMI's Driving Change initiative aims to effect genuine and lasting culture change on research university campuses so that undergraduate students from all backgrounds, particularly those who belong to historically excluded groups, will excel in STEM. Letters of intent due February 7, 2020.

Research Nov 14 2019
Here’s One Way Zika Virus Causes Microcephaly

The mosquito-borne virus can harm fetuses in utero and cause the brain condition microcephaly. Now, scientists have identified a genetic pathway that’s targeted by Zika and revealed one protein’s role in brain development.

Research Oct 31 2019
Measles Virus Infection Destroys Immune System Memory

In humans and macaques, measles infection wipes out antibodies to previous pathogens and could make individuals more susceptible to disease. Until now, such long-term consequences of measles had been unknown.

Research Oct 18 2019
Whole Genome Sequencing Could Help Save Pumas from Inbreeding

The first complete genetic sequences of individual mountain lions point the way to better conservation strategies for saving threatened populations of the wild animals.

Webcast Oct 14 2019
Research Assessment Reform Meeting, Oct 21-22

HHMI and the San Francisco Declaration on Research Assessment (DORA) are convening a diverse group of stakeholders from across academia to consider how to improve research assessment policies and practices. All are invited to livestream the keynote, panel, and plenary talk sessions.

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