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HHMI - Howard Hughes Medical Institute

At the Howard Hughes Medical Institute, we believe in the power of individuals to advance science through research and science education, making discoveries that benefit humanity. Learn more about how we move science forward. James Bardwell Investigator »
INSTITUTE May 26 2022
New Program Pledges $1.5 Billion for Early Career Faculty Committed to Diversity, Equity, and Inclusion

The Freeman Hrabowski Scholars Program will support up to 150 early career scientists for their research and their efforts to create labs in which everyone can thrive. Applications to the program are open now.

Research Jun 10 2022
Scientists Have Found Neurons that Control Some Symptoms of Sickness

Feeling ill is about both the body and the brain. Now scientists have identified a group of neurons in mice that has ultimate control over symptoms such as fever and behaviors like seeking out warmth.

Research Jun 09 2022
Anti-Aging Clues Lurk in Lysosomes, the Recycling Centers of the Cell

Scientists have discovered that lysosomes in roundworms produce molecules that allow cells to ‘talk’ to one another about aging, coordinating the process across the entire organism.

Research May 18 2022
Spying on Thousands of Neurons in the Brain’s Vision Center Simultaneously

Neurons across eight areas of the brain team up to process visual information. Researchers have now documented these neurons’ activity at a breadth and resolution never before reported.

Research May 11 2022
Structure of ‘Gliding Bird’ Plant Protein Could Lead to Better Crops

When pathogens attack, the NPR1 protein steps in to control a plant’s immune response. Scientists have now figured out what the protein looks like and how it works – a possible boon for agriculture.

Research May 05 2022
Cutting Calories and Eating at the Right Time of Day Leads to Longer Life in Mice

In a study that followed hundreds of mice over their lifespans, calorie restriction combined with time-restricted eating boosted longevity.

Research Mar 31 2022
Complete Human Genome Deciphered for the First Time

Twenty years after scientists first reported reading the human genome, the Telomere-to-Telomere consortium has now unveiled a complete version. Their work uncovered hundreds of new genes and opens the door to new insights into evolution and disease.

Research Mar 30 2022
Discovery of How Hyaluronic Acid Is Made Could Spur New Therapeutics

For over two decades, scientists have puzzled over how vertebrates make the essential polysaccharide hyaluronic acid, which has broad medical applications. One team took a different tack and solved the mystery.

Research Mar 10 2022
After More than 20 Years, Scientists Have Solved the Full-Length Structure of a Janus Kinase

More than two decades of effort went into a project that has now revealed the structure of a crucial signaling molecule, opening the door to new and better drugs for some cancers.

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INSTITUTE May 26 2022
New Program Pledges $1.5 Billion for Early Career Faculty Committed to Diversity, Equity, and Inclusion

The Freeman Hrabowski Scholars Program will support up to 150 early career scientists for their research and their efforts to create labs in which everyone can thrive. Applications to the program are open now.

Research Jun 10 2022
Scientists Have Found Neurons that Control Some Symptoms of Sickness

Feeling ill is about both the body and the brain. Now scientists have identified a group of neurons in mice that has ultimate control over symptoms such as fever and behaviors like seeking out warmth.

Research Jun 09 2022
Anti-Aging Clues Lurk in Lysosomes, the Recycling Centers of the Cell

Scientists have discovered that lysosomes in roundworms produce molecules that allow cells to ‘talk’ to one another about aging, coordinating the process across the entire organism.

Research May 18 2022
Spying on Thousands of Neurons in the Brain’s Vision Center Simultaneously

Neurons across eight areas of the brain team up to process visual information. Researchers have now documented these neurons’ activity at a breadth and resolution never before reported.

Research May 11 2022
Structure of ‘Gliding Bird’ Plant Protein Could Lead to Better Crops

When pathogens attack, the NPR1 protein steps in to control a plant’s immune response. Scientists have now figured out what the protein looks like and how it works – a possible boon for agriculture.

Research May 05 2022
Cutting Calories and Eating at the Right Time of Day Leads to Longer Life in Mice

In a study that followed hundreds of mice over their lifespans, calorie restriction combined with time-restricted eating boosted longevity.

Research Mar 31 2022
Complete Human Genome Deciphered for the First Time

Twenty years after scientists first reported reading the human genome, the Telomere-to-Telomere consortium has now unveiled a complete version. Their work uncovered hundreds of new genes and opens the door to new insights into evolution and disease.

Research Mar 30 2022
Discovery of How Hyaluronic Acid Is Made Could Spur New Therapeutics

For over two decades, scientists have puzzled over how vertebrates make the essential polysaccharide hyaluronic acid, which has broad medical applications. One team took a different tack and solved the mystery.

Research Mar 10 2022
After More than 20 Years, Scientists Have Solved the Full-Length Structure of a Janus Kinase

More than two decades of effort went into a project that has now revealed the structure of a crucial signaling molecule, opening the door to new and better drugs for some cancers.

Science Forward
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