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Pardis Sabeti works in computational genetics and infectious disease with two main goals. First, Sabeti and her team develop methods and tools that can be easily leveraged by investigators to open new fields of inquiry in human genome biology and medicine. Second, they synthesize insights and integrate tools from widely varying fields – such as human genomics, viral sequencing, information theory, rural disease surveillance, and education efforts in West Africa — to create comprehensive approaches for detecting, containing, and treating deadly viral diseases. Their efforts include responses to spread of the Ebola, Zika, Lassa, mumps, and COVID-19 viruses.