HomeOur ScientistsDavid G. Schatz

Our Scientists

David G. Schatz, PhD
Investigator / 1991–Present

Scientific Discipline

Biochemistry, Immunology

Host Institution

Yale University

Current Position

Dr. Schatz is also a professor of immunobiology and of molecular biophysics and biochemistry at Yale School of Medicine.

Current Research

Generating a Diverse Repertoire of Antigen-Specific Receptors During Development of the Immune System

David Schatz is interested in understanding the mechanism, regulation, and evolution of the processes that assemble and diversify antigen receptor genes, reactions known as V(D)J recombination and somatic hypermutation. These reactions are essential for the development of the immune system; their mistargeting contributes to genome instability and the development of lymphomas and leukemias. A major goal of Dr. Schatz's research is to understand how these reactions are targeted and the causes of such mistargeting.
RAG and its DNA substrate...

Biography

Dr. Schatz is also Professor of Immunobiology and of Molecular Biophysics and Biochemistry at Yale School of Medicine. He received undergraduate degrees in molecular biophysics and biochemistry from Yale University and in philosophy and…

Dr. Schatz is also Professor of Immunobiology and of Molecular Biophysics and Biochemistry at Yale School of Medicine. He received undergraduate degrees in molecular biophysics and biochemistry from Yale University and in philosophy and politics from Oxford University. His Ph.D. degree and postdoctoral training were done with David Baltimore at the Massachusetts Institute of Technology and the Whitehead Institute for Biomedical Research.

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Education

  • BS, MS, Molecular Biophysics and Biochemistry, Yale University
  • MA, Philosophy and Politics, Oxford University
  • PhD, biology, Massachusetts Institute of Technology

Awards

  • Rhodes Scholar
  • MERIT Award, National Institutes of Health
  • AAI-BD Biosciences Investigator Award
  • Presidential Faculty Fellow Award, National Science Foundation
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Memberships

  • American Academy of Arts and Sciences
  • American Association for Advancement of Science