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André Hoelz, PhD
HHMI Faculty Scholar / 2016–Present
Andre Hoelz, PhD

Institution

California Institute of Technology

Research Summary

To enable detailed studies of how molecules enter and exit cell nuclei – and how disruption of that process contributes to disease – André Hoelz is focusing on the nucleus's only gateway: the nuclear pore complex. He is developing an atomic-level model of the mega assembly, which is made up of about a thousand proteins, and working toward reconstituting it in the test tube.