RESEARCH NEWS
FROM HHMI

Early-to-Bed Mouse Illuminates Workings of Circadian Clock
(01.12.07)
Genetically altered mice that mimic human sleep-wake patterns offer opportunities to understand sleep cycles.

Researchers Find the Snooze Button
(06.08.06)
With help from some drowsy fruit flies, researchers have identified a region of the fruit fly's brain that is crucial to controlling sleep.

Researchers Identify Cause of "Early Bird" Sleep Disorder
(03.31.05)
A few rare people who consistently nod off early, then wake up wide-eyed much before dawn, can blame a newly-found mutant gene for their sleep troubles.

Brain Circuit May Permit Scientists to Eavesdrop on Memory Formation
(10.07.04)
HHMI researchers have identified a circuit in the brain that appears crucial in converting short-term memories into long-term memories.

HHMI SCIENTISTS AND SLEEP & MEMORY

Emmanuel Mignot

Louis J. Ptáček

Erin M. Schuman

Amita Sehgal

FROM THE HHMI BULLETIN

Memories Are Made
Like This
Researchers believe they are deciphering the mysteries of sleep, particularly its role in forging memories.

Man's Best Model
Emmanuel Mignot is not prepared to let sleeping dogs lie.

FROM BIOINTERACTIVE

Holiday Lectures on Science: Clockwork Genes

FROM ASK A SCIENTIST

Metabolism and Sleep

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HHMI Bulletin: May 2008

Cover Story: Teaching Young Biologists New Tricks
Long the science where math mattered less, biology increasingly demands powerful quantitative skills. Teaching students the math they'll need, though, is more than just 1+1=2.

Invisible Barriers
Children with the subtlest form of autism suffer social isolation; those with more severe disease face a much tougher road. New genetic clues put the spotlight on the communication hubs of the brain's neurons–the synapses.

Genetic Balancing Act
Animals have evolved intricate ways to ensure that gene activity is the same in males and females despite the inherent imbalance of X chromosomes.

Sources of Renewal
As scientists learn more about how to produce and manipulate stem cells–amid high expectations and close scrutiny–no one is ready to choose any one approach over another.