RESEARCH NEWS
FROM HHMI

MicroRNAs Intimately Involved in Cancer
(06.09.05)
HHMI investigators have established that tiny RNAs provide a novel genetic route to the initiation of some forms of cancer.

Genetic Tool Reaps Rich Harvest
(04.08.05)
In one fell swoop, scientists have increased from dozens to hundreds the number of known genes that control crucial steps in the development of many organisms from fruit flies to humans.

New RNA Libraries Can Inactivate Human Genes Selectively
(03.25.04)
Researchers have generated large RNA libraries that can be used to turn off individual human and mouse genes to study their function.

Researchers Adapt RNAi to Study Gene Function on a Large Scale
(02.06.04)
HHMI researchers characterized the role in growth and viability of nearly all the genes in the genome of the fruit fly.

Paralyzed Worms Add Pieces to the Puzzle of RNA Interference
(09.15.00)
HHMI researchers pinpoint several genes involved in RNA interference.

HHMI SCIENTISTS AND RNAi

David Bartel

Brenda Bass

Stephen Elledge

H. Robert Horvitz

Scott Lowe

Craig Mello

Norbert Perrimon

FROM THE HHMI BULLETIN

A World Apart
A group of scientists with mammoth imaginations and the best biotech tools is piecing together a view of a prehistoric world where RNA ruled.

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HHMI Bulletin: November 2008

Cover Story: The Meiosis Dance
Researchers are finally learning the molecular steps of a chromosome shuffle that's been watched from afar for centuries.

Lab Lessons
If hands-on is the way to teach science, hands-on in a real scientist's lab has got to be the ultimate, right? More programs think so, and they are finding ways to make it happen for high school students.

Carving Out Her Niche
Judith Kimble's engaged style has made for a vibrant career unraveling mechanisms that control stem-cell development—and some interesting airplane chats.

Science 2.0: You Say You Want a Revolution?
The collaborative online tools people are using in other parts of their lives, such as Facebook, YouTube, and blogs, are roiling the disciplined world of scientific communication.