RESEARCH NEWS
FROM HHMI

MicroRNAs Intimately Involved in Cancer
(06.09.05)
HHMI investigators have established that tiny RNAs provide a novel genetic route to the initiation of some forms of cancer.

Genetic Tool Reaps Rich Harvest
(04.08.05)
In one fell swoop, scientists have increased from dozens to hundreds the number of known genes that control crucial steps in the development of many organisms from fruit flies to humans.

New RNA Libraries Can Inactivate Human Genes Selectively
(03.25.04)
Researchers have generated large RNA libraries that can be used to turn off individual human and mouse genes to study their function.

Researchers Adapt RNAi to Study Gene Function on a Large Scale
(02.06.04)
HHMI researchers characterized the role in growth and viability of nearly all the genes in the genome of the fruit fly.

Paralyzed Worms Add Pieces to the Puzzle of RNA Interference
(09.15.00)
HHMI researchers pinpoint several genes involved in RNA interference.

HHMI SCIENTISTS AND RNAi

David Bartel

Brenda Bass

Stephen Elledge

H. Robert Horvitz

Scott Lowe

Craig Mello

Norbert Perrimon

FROM THE HHMI BULLETIN

A World Apart
A group of scientists with mammoth imaginations and the best biotech tools is piecing together a view of a prehistoric world where RNA ruled.

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HHMI Bulletin: May 2009

Cover Story: Cellular Neatniks
The architecture that carefully arranges our unruly strands of DNA has more control over gene expression than imagined.

Three's a Crowd, Ten's a Posse
One group of young scientists at Brandeis University has an unbeatable support network in all areas of college life.

Fifty Stories
Top early career academic scientists get six years of support from HHMI to pursue their best ideas.

Better Than Tea Leaves
Will mathematical models that consider climate change, disease agents, and human immunity—as a start—offer a reliable way to anticipate the next outbreak of cholera or malaria?