RESEARCH NEWS
FROM HHMI

MicroRNAs Intimately Involved in Cancer
(06.09.05)
HHMI investigators have established that tiny RNAs provide a novel genetic route to the initiation of some forms of cancer.

Genetic Tool Reaps Rich Harvest
(04.08.05)
In one fell swoop, scientists have increased from dozens to hundreds the number of known genes that control crucial steps in the development of many organisms from fruit flies to humans.

New RNA Libraries Can Inactivate Human Genes Selectively
(03.25.04)
Researchers have generated large RNA libraries that can be used to turn off individual human and mouse genes to study their function.

Researchers Adapt RNAi to Study Gene Function on a Large Scale
(02.06.04)
HHMI researchers characterized the role in growth and viability of nearly all the genes in the genome of the fruit fly.

Paralyzed Worms Add Pieces to the Puzzle of RNA Interference
(09.15.00)
HHMI researchers pinpoint several genes involved in RNA interference.

HHMI SCIENTISTS AND RNAi

David Bartel

Brenda Bass

Stephen Elledge

H. Robert Horvitz

Scott Lowe

Craig Mello

Norbert Perrimon

FROM THE HHMI BULLETIN

A World Apart
A group of scientists with mammoth imaginations and the best biotech tools is piecing together a view of a prehistoric world where RNA ruled.

Subscribe to the HHMI Bulletin

HHMI Bulletin: February 2010

Cover Story: Ahead of the Curve
Jack Szostak is drawn to uncharted territory. His curiosity and big thinking have earned him a Nobel Prize.

Cover Story: View from the Top
An uncanny way with crystals led Tom Steitz to a clear view of the ribosome's structure—and to the Nobel Prize.

The China Connection
China-born, U.S.-trained scientists are helping foster innovation and revitalize research in their native land.

A Matter of Equilibrium
Researchers are getting at the cell's busy internal membranes by studying human diseases.