RESEARCH NEWS
FROM HHMI

Battle of the Bubbles May Have Sparked Evolution
(09.03.04)
The first survival-of-the-fittest competition was likely a physical duel between fatty bubbles stuffed with genetic material.

Clays May Have Aided Formation of Primordial Cells
(10.24.03)
HHMI researchers discover that clays may have played a pivotal role in the evolution of the first living cells.

Evidence that a Ribozyme Evolved Multiple Times
(11.01.01)
HHMI investigators report that the hammerhead ribozyme might have evolved multiple times.

Researchers Evolve New Proteins in the Test Tube
(04.05.01)
HHMI researchers subject proteins derived from 400 trillion random DNA sequences to natural selection in the test tube.

HHMI SCIENTISTS AND ARTIFICIAL LIFE

David Bartel

Jack W. Szostak

Rachel Green

FROM THE HHMI BULLETIN

A World Apart
A group of scientists with mammoth imaginations and the best biotech tools is piecing together a view of a prehistoric world where RNA ruled.

Engineering the Cell
Adam Arkin sees the cell as a mechanical system.

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HHMI Bulletin: August 2008

Cover Story: Thinking Like an Engineer
Scientists are applying the tools and approaches of engineering to solve some practical problems and fathom the basic nature of things.

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HHMI's newest investigators are willing to sidle up to risk. Their approaches to research—and life—dispel many of the myths about the lone, detached scientist.

The Unintentional Scientist
Joan Massagué was having too much fun to notice he was building a career—and solving problems of cell signaling and cancer metastasis.

Nerve Cell Navigation
Nerve cells exploit a complex set of cues to wire up properly in developing organisms. A closer view of this process may ultimately help to correct neurological problems that lead to schizophrenia and other disorders.