Putting the Brakes on Cancer (May 2007) By reactivating p53—a renowned tumor-suppressor gene—researchers are stopping even advanced cancers in mice.
Bringing Down Cancer's House of Cards (February 2008)
Defining an elaborate yet fragile control pathway offers a new strategy for toppling many cancers.
Cover Story:Rational Exuberance
A Nobelist shares the secrets to his longevity in the lab.
A Structural Revolution
A quarter century ago, structural biology hit a wall. HHMI created a way to break through.
One Foot in Front of the Other
Inside cells, specialized proteins march down a network of highways carrying machinery and messages. Researchers are learning how they manage it.
A Happy Oasis
Once Sangeeta Bhatia created her lab the way she wanted-as a supportive, intellectually challenging environment-the creative juices began to flow.