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Professor Sansonetti received his M.D. in 1979 from the University of Paris. From 1979 to 1981, he conducted research in the Department of Enteric Infections at the Walter Reed Army Institute of Research in the United States. He is a Chevalier de la Légion d'Honneur and received the Prix d'Excellence Jacques Monod en Biologie Moléculaire, the Prix AGIR du Conseil Pasteur-Weitzmann, the Grand Prix de l'Académie de Médecine, the Prix Louis Jeantet de Médecine, and the Robert Koch Prize and Medal. He is a member of the French Academy of Science and a corresponding member of the French Academy of Medicine. He was elected foreign member of the Max-Planck-Society and was elected to the American Academy of Arts and Sciences. He is currently professor at the Institute Pasteur and head of the Unité de Pathogénie Microbienne Moléculaire at the Pasteur Institute of Paris. He recently was appointed Chair of Microbiology and Infectious Diseases at the Collège de France, where he will teach his discipline in addition to pursuing his research at Institute Pasteur. This is his second HHMI award.
RESEARCH ABSTRACT SUMMARY:
Philippe Sansonetti studies Shigella, Gram-negative bacteria that cause dysentery. His goal is to decipher the molecular and cellular bases of Shigella's rupture, invasion and inflammatory destruction of the intestinal lining. He also is analysing the mechanisms of immunity against Shigella, hoping to use his findings to develop vaccine candidates.
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Photo: Soubert Christophe
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