My doctoral and postdoctoral research focused primarily on applying functional genetic and genomic approaches in different arthropod models, including Drosophila melanogaster, Tribolium castaneum and Parhyale hawaiensis, to study the role of Hox genes in appendage development and evolution. These studies provided the entry point into my long-term research on the molecular and cellular mechanisms that control tissue and organ morphogenesis during animal development.
Having a strong experimental background in developmental genetics and molecular cell biology, I appreciate that the powerful synthesis of concepts and methodologies from biology, physics, and computer vision, as well as the interplay between theory and experiment, are necessary to fully comprehend the dynamics of developing living systems. Accordingly, my ongoing research couples functional genetic approaches with extensive multiview light-sheet microscopy recordings and sophisticated image analysis tools that will allow gene regulatory network dynamics, cell lineages, and a variety of cell behaviors to be analyzed in vivo during cell fate specification and in the context of developmental morphogenesis.
As of September 12, 2013