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Dr. Ziff is Professor of Biochemistry at New York University School of Medicine. He received his bachelor's degree in chemistry from Columbia University and his Ph.D. degree in biochemistry from Princeton University. He studied DNA structure with Fred Sanger at the Medical Research Council Laboratory of Molecular Biology in Cambridge, England. He later conducted research on DNA tumor viruses at the Imperial Cancer Research Fund Laboratory, London, and on gene expression by adenoviruses in the Department of Molecular Cell Biology at the Rockefeller University. Dr. Ziff then joined the New York University School of Medicine and began to study the mechanisms that control cellular responses to growth factors, the differentiation of neurons, and more recently, the architecture of excitatory synapses and the regulation of glutamate receptors.
RESEARCH ABSTRACT SUMMARY:
Edward Ziff's laboratory studies the regulation of AMPA receptors, glutamate-regulated cation channels that are found at excitatory synapses in the central nervous system. The lab has cloned a group of proteins that bind to the cytoplasmic domains of AMPA receptor subunits and is studying their contributions to receptor transport and the regulation of synapse strength.
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Photo: Courtesy of New York University School of Medicine
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