Dr. Wrana is an investigator in the Department of Molecular Biology and Cancer at the Samuel Lunenfeld Research Institute, Mount Sinai Hospital, and a professor in the Department of Medical Genetics and Microbiology at the University of Toronto, Canada. He received a Ph.D. in biochemistry in 1991 from the University of Toronto and did postdoctoral work in the United States at the Memorial Sloan-Kettering Cancer Center in New York. He was awarded the William E. Rawls Prize from the National Cancer Institute of Canada, the Premier’s Research Excellence Award from the Government of Ontario, the CIHR Investigator Award from the Medical Research Council of Canada, the Allan Bruce Robertson Young Investigator Award, the Merck Frosst Prize, and the Paul Marks Prize for Cancer Research; in 2004, he was named a McLaughlin Scholar by the R. Samuel McLaughlin Centre for Molecular Medicine.

Using high-throughput proteomics and genetic tools, Jeffrey Wrana's research program seeks to understand how morphogen cell signaling pathways and the higher organizational structure, or network, into which they are integrated controls cell behavior in development and cancer.