|
Dr. Radi received his M.D. in 1988 and his Ph.D. in biochemistry in 1991 from the Universidad de la República in Montevideo, Uruguay. From 1989 to 1991, he worked in the Departments of Anesthesiology and of Biochemistry of the University of Alabama at Birmingham, where he was named honorary professor in 1998. He was awarded the title of First Level Investigator for Biology and Chemistry by PEDECIBA–Uruguay. He was a senior Fulbright Scholar (1998) and a fellow of the Guggenheim Foundation (2003–2004). In 2004, he was named a member of the Academy of Sciences for the Developing World (TWAS) and a foreign member of the Argentinian Academy of Sciences; in 2006, he became a foreign member of the Brazilian Academy of Sciences and president of the Society for Free Radical Biology and Medicine. He is currently a professor in the Department of Biochemistry at the Facultad de Medicina, Universidad de la República of Uruguay. This is his second HHMI award.
RESEARCH ABSTRACT SUMMARY:
Rafael Radi is testing the hypothesis that during mammalian infection with Trypanosoma cruzi, the parasite that causes Chagas disease, the interplay between the metabolism of the amino acid L-arginine and oxidation-reduction processes of both the parasite and host target cells determine cell survival or death. He is testing the hypothesis using biochemical, cellular, and in vivo model systems. The finding may permit development of novel and effective infection control strategies.
View Research Abstract
Photo: David Rolls
|
