Suzanne M. Jan de Beur, M.D.
Research Scholar, 1989-1990
Assistant Professor of Medicine
The Johns Hopkins University School of Medicine

"An early exposure to research in high school sparked an unshakable curiosity about the basic mechanisms of human disease that continues to drive me. My experience as an HHMI-NIH Research Scholar was instrumental in directing me to a career encompassing both an understanding of disease at the clinical and molecular level and the translation of that understanding back to the bedside.

After completing two years of medical school, I wanted to explore the ways in which a medical career could interface with basic research. The HHMI-NIH Research Scholars Program offered an unparalleled opportunity. During this intensive year, I worked in the vibrant and productive laboratory of Dr. Ron Crystal. The focus of our investigation was in vivo gene transfer to lung epithelium as the groundwork for delivering genes to the lung in the treatment of cystic fibrosis.

The atmosphere at the Cloister complemented and extended my laboratory experience. The Cloister was alive with curiosity and enthusiasm for research that was fueled by outstanding peers with common interests and career goals. Scientific discussion and exchange of ideas took place in every possible venue including the weekly informal science sessions, the dinner table, fitness center, the lounge, and the lawn during croquet games. The program provided unequaled opportunities to engage distinguished scientists. The Monday night lecture series schedule read like a "Who's Who" of science. At the American Society of Clinical Research meeting, the Scholars attended a lunch with internationally renowned scientists. I remember having lunch flanked by Michael Brown and Joseph Goldstein!

My experience as an HHMI-NIH Research Scholar was of tremendous benefit personally and professionally. Broad exposure to many scientific fields taught me to ask important questions, and sharpened my ability to understand how to approach problems and to critically evaluate my work and the work of others. I learned how to efficiently formulate and communicate my ideas through presentation of my work at local and national meetings. I discovered that a successful scientist needs excellent colleagues, mentorship and a vibrant research environment.

After graduating from Cornell Medical College, I completed residency in internal medicine and subspecialty training in endocrinology at The Johns Hopkins University School of Medicine where I am now an Assistant Professor of Medicine. My laboratory focuses on the molecular basis of hormonal regulation of phosphate homeostasis in inherited and acquired hypophosphatemic disorders with the objective of understanding normal physiologic phosphate regulation. The valuable experience I gained as a Research Scholar substantially contributed to my success in competing for a five-year career development award from the NIH. The Cloister Program started me on the path to becoming a physician-scientist, cultivated my research skills, and exposed me to role models and mentors that continue to guide me on my journey to understand human disease at the most basic level."