Matthew Warman is interested in understanding how the human skeleton develops and maintains itself throughout a lifetime of use. As a clinician-scientist, his research in skeletal biology attempts to traverse the interface between basic science and clinical application.
Genetic Skeletal Disease
Summer students are paired with postdoctoral fellows. Students are given a focused, but important, question related to specific skeletal diseases that need to be addressed scientifically. Examples of such questions include the following: Can the accuracy of genetic or biochemical testing for the disease be improved? Can a cell biologic or animal model of the disease be used to better understand the pathophysiology of the human disease? Can a rare genetic disease provide fundamental insights into pathologic processes that give rise to more common diseases?