EXROP Projects: Joseph L. DeRisi

Joseph L. DeRisi

Summary

Joseph DeRisi employs a highly interdisciplinary approach, combining genomics, bioinformatics, biochemistry, and bioengineering to study parasitic and viral infectious diseases in a wide range of organisms. 

Scientific Disciplines: Molecular Biology, Virology
Organisms: Parasites, Viruses
Summer Lab Size: 21
Local Summer Program: Summer Research Programs
Program Dates: May 27-August 1, 2014 (Dates for 2015 should be similar)

Genomics and Infectious Disease

Our lab is dedicated to the study of infectious disease, including the causative agent of the most deadly form of human malaria, Plasmodium falciparum, and a wide range of viral pathogens. In particular, we use a variety of high-throughput genome-wide approaches, robotics, microfluidics, and bioinformatics to dissect the molecular physiology of the malaria parasite with respect to gene regulation, messenger RNA dynamics, and evolution of drug resistance. We are developing and applying similar strategies to examine the role of viruses in diseases of unknown etiology and the evolution of RNA viruses, including arenavirus, enterovirus, and many more. Throughout all of these projects, we pursue a highly interdisciplinary approach, consisting of expertise in parasitology, structural biology, genomics, bioinformatics, and virology, to develop new technologies and analysis approaches.

Scientist Profile

Investigator
University of California, San Francisco
Molecular Biology, Virology