Duojia Pan studies the molecular and developmental pathways that control how organ size is determined in different organisms and the way these mechanisms regulate tissue homeostasis in normal and pathological conditions.
Characterization of Genes Controlling Organ Size
My lab is interested in using the fruit fly Drosophila as a model to reveal novel genes and pathways that regulate organ size in development. Our research has led to the discovery of signaling pathways that play conserved roles in the growth of mammalian organs. In this project, students will conduct genetic screens for growth control genes in Drosophila and conduct functional studies of the genes identified from such screens. Students will gain experience with fly genetics and molecular biology. These positions offer exciting opportunities to join a research team working in the areas of developmental biology, cell signaling, and cancer biology.