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Featured inside this issue of the magazine—I Am a Scientist: The EXROP program has helped hundreds of underrepresented minorities identify as researchers, a key step toward a science career.
Also in this issue:
A Structural Toolbox: No longer content with static snapshots, biologists are using a...
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In six interactive virtual labs, identify bacteria, examine heart patients, probe the nervous system, assay antibodies, study circadian rhythms, and analyze evolution in action in stickleback fish.
Bacterial ID Lab: Use DNA sequencing techniques to identify deadly pathogens.
Cardiology Lab:...
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"Evolving Switches, Evolving Bodies" and "Got Lactase? The Co-evolution of Genes and Culture," are the fourth and fifth films in the series "The Making of the Fittest," which features unforgettable examples of the evolutionary process in action. Each film is an adventure of discovery—from the...
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Modern humans have lived on Earth for only the past 200,000 years—not even a blink of an eye in the history of a planet that is about 4.6 billion years old. Scientists have discovered a rich fossil record of animal evolution going back more than 600 million years and a much richer one of microbial...
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The Indispensables: Problem solvers, shelf stockers, bench scientists, record keepers, machine fixers, weekend warriors, den mothers, old hands, fresh eyes, mentors, managers. Every research lab has behind-the-scenes specialists without whom modern science could not get done. Also in this issue...
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The disappearance of the dinosaurs at the end of the Cretaceous period posed one of the greatest, long-standing scientific mysteries. This three-act film tells the story of the extraordinary detective work that solved it. Representing a rare instance with which many different scientific...
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When Darwin proposed that humans evolved from a common ancestor with the great apes, he lacked fossil evidence to support his idea. One hundred and fifty years later, the evidence for human evolution is plentiful and growing, including detailed molecular genetics data, an impressive fossil record...
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Year of Chemistry: Chemists fascinated by the complexity of biology are solving problems in neuroscience, immunology, and cell signaling. Also in this issue:
Have Microscope, Will Travel: Biology students and faculty immersed in summer courses at Woods Hole get their hands on a remarkably...
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A trilogy of short films featuring unforgettable examples of the evolutionary process in action. Each film is an adventure of discovery—from the deserts of the American Southwest, to the icy Antarctic, and the lowlands and highlands of Eastern Africa, where fascinating creatures and pioneering...
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In this report: 15 new plant scientists, shutting off anxiety, what it takes to control HIV naturally, new open access journal, microscopy's new world, Jeffrey Friedman receives Lasker Award, targeting cancer stem cells, missing DNA makes us human, RNA-DNA differences uncovered, documentary film...
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Why is dengue fever becoming a worldwide health threat? What other epidemics are on the horizon? How can we detect and counter emerging infectious diseases? In four presentations, Dr. Joseph L. DeRisi and Dr. Eva Harris explain how they use both simple and sophisticated technologies to detect and...
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Going Deep: Researchers are diving into the complicated world of the human gut. Also in this issue:
Two Roads to an End: Though separated by an ocean, Christopher Plowe and Abdoulaye Djimdé are bound by their determination to stop malaria's global toll;
Into the...
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Light Moves: Light is becoming the tool of choice for researchers who want to precisely manipulate neurons and other cells in "Light Moves." Also in this issue:
A Kaleidoscopic View: Elaine Fuchs brings an eye for the creative in the many-colored facets of her life and work;
Silver...
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In this report: new melanoma drug shows promise, transforming science education at all levels, Schmoke elected chairman of the HHMI trustees, evolution's art, our biased genes, the molecular origins of a rare eye disorder, Bishai named head of new TB-HIV institute, Nobels honor Szostak and Steitz...
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What medical secrets do venomous snails hold? How can listening in on bacterial conversations help develop new antibiotics? In four presentations, Dr. Bonnie L. Bassler and Dr. Baldomero M. Olivera reveal how a deeper understanding of nature and biodiversity informs their research into new...
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Problems during pregnancy burden too many newborns with lifelong disabilities. Researchers are finding clues to a safer nine months, and a bright future in "The Most Vulnerable Patients." Also in this issue:
A social conscience rooted in the Deep South moves Kerry Ressler, a psychiatrist and...
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In this report: Tjian takes the helm, Tsien receives the Nobel Prize, K-RITH breaks new ground, early career honors, new training for future docs, genes help cancer spread, keeping microbes mum, a better memory-boosting drug, gene network buoys cancer, when the brain's wiring fails, financials.
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Is there any more to mind than the brain? Does experience shape the way our brain develops? When we learn something new is our brain physically altered? In four presentations, Dr. Thomas M. Jessell and Dr. Eric R. Kandel help us puzzle out how the brain is organized, how it develops, how it...
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Long the science where math mattered less, biology increasingly demands powerful quantitative skills. Teaching students the math they need, though, is more than just 1 + 1=2. Read about how real-world math problems may make students better biologists. Also in this issue:
Children with the...
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In this report: asking big questions, making creative connections, putting new approaches to the test, probing complexity, the year in review, financials. 88 pages.
The HHMI annual report reviews accomplishments in biomedical research and science education and provides a summary of the Institute's...
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Nobel laureate Mario Capecchi has the confidence to march to his own drummer and the patience to focus on the long view. Read about Capecchi's long-term view in "Guided by His Inner Compass." Also in this issue:
Studying the form and function of this cellular sac of enzymes is leading to...
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Can AIDS be cured? Why has it been so hard to develop a vaccine against HIV? How are new medicines revolutionizing AIDS treatment? In four presentations, Dr. Bruce D. Walker and Dr. Bisola O. Ojikutu explain why understanding HIV evolution is critical to fighting AIDS.
This DVD set includes...
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Scientists with technical ingenuity are opening new vistas into the finer points of the cell.To true tinkerers the limits of the present are never permanent barriers, merely offers they can't refuse in "A Different Mindset." Also in this issue:
Sydney Brenner's hopes for understanding the brain—...
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Can a pill be the solution to the diabesity epidemic? Does the answer lie in "Exercise in a Pill?" Also in this issue:
Researchers believe they are deciphering some of the mysteries of sleep, particularly its role in forging new memories in "Memories Are Made Like This";
HHMI professor, Louis...
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In this report: Thinking like a scientist, new ways to visualize what can't be seen, the boundless potential of stem cells, transforming science with nano-sized tools, and building communities of learning. 80 pages.
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Leading evolution educator Ken Miller discusses the controversy surrounding the teaching of evolution, presents compelling evidence for evolution and reasons why "intelligent design" is not scientific. The presentation also features Dr. Miller's responses to questions from a live audience of high...
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What are embryonic stem cells? Why are they potent? How do they differ from adult stem cells? Are embryonic development and regeneration intimately connected? In four presentations, Dr. Douglas A. Melton and Dr. Nadia Rosenthal discuss how stem cells may hold the key for curing diseases and...
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This book takes you step by step through the behind-the-scenes activities that result in a successful training event.
You may use, copy, or distribute these publications or any excerpts provided that use is for noncommercial educational purposes.
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Based on courses held in 2002 and 2005 by the Burroughs Wellcome Fund and HHMI, this book is a collection of practical advice and experiences from seasoned biomedical investigators. The second edition contains three new chapters on laboratory leadership, project management, and teaching and course...
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In this report: Pursuing a scientific vision at the new Janelia Farm Research Campus, finding unexpected paths to discovery in biomedical research, and transforming the educational landscape with innovative grant programs. 74 pages.
The HHMI annual report reviews accomplishments in biomedical...
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How has the amazing diversity of plants and animals evolved? What can fossils, butterflies, and stickleback fish tell us about the deep common ancestry of all living forms? In four presentations, Dr. Sean B. Carroll and Dr. David M. Kingsley explore how key developmental genes, natural selection,...
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In this report: Development of novel animal models, discovery of new techniques and tools, elucidation of complex structures, and sharing knowledge to support science education. 70 pages.
The HHMI annual report reviews accomplishments in biomedical research and science education and provides a...
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Scientists are unraveling the mechanisms that dictate how the brain and body regulate weight. In four presentations, Dr. Ronald M. Evans and Dr. Jeffrey M. Friedman discuss what the latest advances in genetic and molecular research tell us about why some people are hefty while others are lean....
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In certain families, small genetic variations bring good health and long life. Can researchers use this knowledge to benefit us all? Also in this issue:
Investigating the roots of heart disease, physician-scientist Helen Hobbs applies what she learns in the clinic to her research in the lab;...
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Biomedical scientists can gain essential insights from patients that help move their research in new directions. In four lectures, Dr. Bert Vogelstein and Dr. Huda Y. Zoghbi discuss how their patients have led them to a deeper understanding of the genetic and molecular bases of cancer and...
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Biomedical scientists can gain essential insights from patients that help move their research in new directions. In four lectures, Dr. Bert Vogelstein and Dr. Huda Y. Zoghbi discuss how their patients have led them to a deeper understanding of the genetic and molecular bases of cancer and...
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The sequencing of the human genome has set the stage for a vast revolution in the biomedical sciences. In four presentations featuring state-of-the-art animations and compelling graphics, Dr. Stuart L. Schreiber and Dr. Eric S. Lander open a window onto the fast-paced world of genomic science and...
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The sequencing of the human genome has set the stage for a vast revolution in the biomedical sciences. In four presentations featuring state-of-the-art animations and compelling graphics, Dr. Stuart L. Schreiber and Dr. Eric S. Lander open a window onto the fast-paced world of genomic science and...
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A curled lip, a furrowed brow—sometimes even a small change in expression can reveal far more than words. Now, a computer program can analyze images of faces as accurately as trained professionals. Also in this issue:
Carlos Bustamante is a self-described "patchwork biophysicist" with an...
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In this report: New HHMI president Thomas R. Cech and his leadership team explore opportunities to advance science and education. 40 pages.
The HHMI annual report reviews accomplishments in biomedical research and science education and provides a summary of the Institute's finances.
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Sophisticated new techniques in molecular biology are allowing scientists to understand, combat, and prevent the spread of infectious diseases. In four lectures, Dr. Donald E. Ganem and Dr. B. Brett Finlay describe the latest advances in understanding how pathogens invade the body and how this...
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RNA can be much more than a passive transmitter of genetic information. It can also act as an enzyme that directly participates in cellular biochemistry. In four lectures, Dr. Thomas R. Cech tells the story of the discovery of RNA catalysis—research that led to his receiving the 1989 Nobel Prize...