Genome Wonderland Gives Way to Daunting Challenges of the Proteome
February 12, 2001— With the task of sequencing the human genome behind them, researchers now face the complexities of the proteome.

Rosetta May Hold Key to Predicting Protein Folding
February 12, 2001— A computational method developed by HHMI investigators predicts the three-dimensional structure of proteins with surprising accuracy.

Comparing Genomes Will Illuminate Gene Function
February 12, 2001— Comparing the genomes of humans, fruitflies, worms, plants and yeast may lead to unprecedented insight into how genes function.

Human Disease Gene Survey Yields Underlying Principles
February 12, 2001— HHMI researchers look for underlying principles in human diseases.

Human Genome Analysis Hints at New Proteins Involved in Gene Expression
February 12, 2001— Promising evidence that the completed genome will yield new proteins involved in gene expression.

Molecular Analysis Shows Complexity Behind Cargo Delivery System of Mammalian Cells
February 12, 2001— The complex physiology of mammals is achieved, in part, by fine-tuned regulation of the protein transport system.