Two critical genes that serve as beacons and give cells a much needed sense of direction in the chaotic days of early development have been identified by HHMI researchers at the University of Toronto.
HHMI will challenge research universities to develop compelling new ways to show undergraduate students the excitement and creativity of science by inviting nearly 200 top institutions to compete for individual grants of up to $2.2 million. HHMI plans to award up to $85 million in total grants.
A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs.
HHMI researchers have designed tiny RNA molecules that shut off the gene that causes Huntington’s disease without damaging that gene’s healthy counterpart, which maintains the health and vitality of neurons.
An international scientific challenge is being launched to speed development of new tools that accurately and automatically reconstruct the shape of brain cells from microscopy data.
Researchers have identified a group of genes that influence a person's sensitivity to radiation.
A new type of scaffold for growing human cells mimics conditions inside the body better than flat Petri dishes.
A gene strongly implicated in schizophrenia is essential for normal brain development and the growth of new neurons in the adult brain.
Una mejor protección podría provenir de una vacuna contra el VIH que haga que el cuerpo produzca un “enjambre” de anticuerpos naturales.
Better protection might come from an HIV vaccine that induces the body to produce a "swarm" of natural antibodies.
Scientists have discovered sensory neurons within the antennae that help flies respond to wind.
Small genomes are cheaper to sequence and lack the repetitive "junk" that clutters bigger genomes—but a new study suggests that bigger genomes are better for figuring out how genes are controlled.
Researchers have taken a major step toward developing a better animal model of human AIDS by genetically modifying HIV so that it can infect a species of rhesus monkeys.
Scientists have mapped previously unknown pathways in yeast cells that link the overactivity of a mysterious gene to the death of nerve cells in Parkinson's disease.
A new tool reveals the identity and quantity of every protein produced by a living cell at any given time.
Researchers have identified a marker present in the urine of patients with prostate cancer that indicates whether the cancer is progressing and spreading.
Investigadores han identificado un nuevo marcador biológico que se encuentra presente en la orina de pacientes con cáncer de próstata que indica si el cáncer está progresando y se está diseminando.
HHMI researchers and their colleagues unveil the first comparative map of four primate genomes.
Blood platelets can destroy deadly malaria parasites. But a single dose of aspirin may be enough to thwart their killing power.
Nuevos estudios en ratones sugieren que las plaquetas sanguíneas pueden destruir los mortales parásitos de la malaria. Pero una única dosis de aspirina puede interferir con las plaquetas de forma suficiente como para impedir su poder letal.
The shapes of some of the tiniest cellular structures are coming into sharper focus at Janelia Farm, where scientists have developed a new imaging technology that produces the best three-dimensional resolution ever seen with an optical microscope.
Rajesh Gokhale has created a compound in his lab in India that stops tuberculosis by hitting four of the bacterium's crucial metabolic pathways at the same time.
Researchers have discovered a new form of cellular memory that appears to help immune cells "learn" from past encounters with pathogens so they can combat them more effectively the second time around.
Researchers have created an efficient way to detect genes that have been inappropriately fused together, a type of genetic abnormality that spurs the growth of blood and prostate cancers.
A novel kind of odor-detecting protein may explain some of the gaps in researchers' knowledge of how insects smell.