Health officials have held off from recommending an inexpensive malaria drug for widespread use because of concerns about drug resistance. New research drawn from 10 years of field and laboratory studies suggests the drug may be a safe and effective way to prevent malaria.
HHMI researchers develop tiny life-support packets for therapeutic cells.
A cooperative online game has attracted 50,000 players whose “distributed thinking” has, in some cases, proven more powerful than computers in predicting the structure of proteins.
HHMI has awarded $364,000 to more than double the capacity of a vital repository that is a resource for the worldwide community of scientists who study the fruit fly.
A type of prostate cell that has been largely ignored by cancer researchers can trigger malignant prostate cancer.
Janelia Farm researchers show it takes steady hands to measure the brain activity of a fruit fly while it is walking.
HHMI researchers discover that induced pluripotent stem cells retain a genetic memory of their tissue of origin.
A protein that is already the target of experimental drugs that aim to extend life is now known to play a key role in learning and memory.
An ambitious new analysis in mice demonstrates that for more than 1,300 genes active in the brain, there is a significant bias as to which copy is active—the one inherited from the mother or the one that came from the father.
Researchers have identified signaling pathways by which the normal prion protein switches on the general protein synthesis necessary to promote the growth and development of brain cells.
A new imaging method will allow researchers to study speedy cell processes over hours and days rather than seconds, and to examine how morphological defects arise in developing animals.
Five teams will compete in the final round of an international scientific challenge designed to speed development of new computational tools to accurately and automatically reconstruct the shape of brain cells.
Babies delivered via Cesarean section harbor a different ecosystem of bacteria than babies born vaginally.
Jumping genes, thought to have settled down over millions of years of evolution, may be an ongoing source of genetic variation between individuals.
Moore, COO of HHMI's Janelia Farm Research Campus, will assume the new role in September 2010.
Elementary students get a hands-on—and feet-in—experience that teaches them to develop hypotheses and reach conclusions about the relative health of their community stream.
This year, 116 medical, dental, and veterinary students from 47 schools across the country will take a break from memorizing molecular metabolism and studying drug interactions to spend a year in a lab doing hands-on research.
The mucosal immune system is often the first to tangle with microbial invaders. To better understand it, scientists should focus on the interplay between the mucosal immune system and friendly microbes.
HHMI investigator William Newsome and NYU researcher J. Anthony Movshon are recipients of the 2010 Vision Award.
Schmoke, Dean of the Howard University School of Law, succeeds Hanna H. Gray as Chairman of the Trustees of the Howard Hughes Medical Institute.
Researchers have identified a set of hybrid genes that may accelerate the growth of prostate cancer, gastric cancer, and melanoma.
The prestigious $500,000 Lemelson-MIT Prize honors outstanding mid-career inventors dedicated to improving the world through technological invention and innovation.
A pediatric kidney cancer called Wilms tumor may, with just a few genetic changes, hijack pathways that ordinarily drive development of normal kidney tissue.
HHMI researcher Thomas C. Sudhof shares the 2010 Kavli Prize in Neuroscience with Richard H. Scheller and James E. Rothman.
A new genetic analysis suggests that the strains of influenza circulating in the United States can migrate to the rest of the world.
HHMI and the University of KwaZulu-Natal announce appointment of Bishai as the first permanent director of the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH).
A mysterious swallowing disorder bears similarities to a disease that afflicts parrots and other exotic birds.
A genome-wide search reveals a genetic survival pathway that is switched on in many of the most aggressive glioblastomas.
A unique analysis of environmental contributors to type 2 diabetes has confirmed a link between several pollutants and the disease, while also pointing toward a form of vitamin E as a possible risk factor.
Thirteen HHMI professors with successful science education programs were awarded a total of $9 million over the next four years.
MIT will use part of its $1.8 million HHMI grant to share its online science educational tools with a larger worldwide audience through its OpenCourseWare (OCW) program.
The University of North Texas will use a portion of its first $1.3 million HHMI grant to encourage a successful transition for students from community colleges to the four-year school and expand research opportunities to more students.
The University of Miami is using a portion of its new $1.4 million HHMI grant to spearhead an approach that focuses on preparing undergraduate students from underrepresented backgrounds to succeed in science.
The Science Literacy Program (SLP), funded by an HHMI grant, will help faculty from four departments—chemistry, physics, biology, and geological sciences—transform the classes they offer to non-science majors.
Lehigh's Biosystems Dynamics Summer Institute (BDSI)—a 10-week summer program—places undergraduates, graduate students, and faculty members on interdisciplinary teams to tackle projects such as looking for drugs to treat stress disorders and developing reliable methods to separate cells in the blood for detection of HIV.
High school students across New Mexico have conducted basic genetics experiments with the help of New Mexico State University scientists and a mobile lab that travels to a different high school each week.
A list of the universities that received grants for 2010 through HHMI's Precollege and Undergraduate Science Education Program and the HHMI Professors Program.
To better tailor the premed curriculum to the needs of future physicians, Yale University is developing a cluster of new interdisciplinary courses that devote special focus to the concepts most relevant to medicine.
The University of Missouri, Columbia's interdisciplinary program with the renowned University of Missouri School of Journalism will prepare up-and-coming scientists to communicate with—even educate—the public.
The University of Maryland will use a portion of its new $1.5 million grant to partner with the nonprofit MDBio Foundation to bring its mobile laboratory to high schools throughout the state for one-week visits.
The University of California, Los Angeles will use part of a new $1.2 million HHMI grant to break down artificial boundaries imposed by traditional major requirements to allow students to experience the thrill of the scientific chase.
At Cornell University's popular summer workshops, teachers spend their days sharpening their skills.
At Washington University in St. Louis, freshmen in a special genomics course learn by doing. Working in small teams, they isolated and sequenced the DNA of phages.
The University of Alabama's new grant will create a semester-long introductory seminar that will rotate among three campuses.
With its new HHMI science education grant, the school’s first, Florida International University will create a more hands-on, active learning environment in introductory science courses.
Rice University's program aims to open students’ eyes to the challenges of global health, and help them use the tools of science and engineering to design solutions that are affordable, effective, and culturally appropriate.
University of Pittsburgh’s latest HHMI grant will help improve how science is taught and will be used to expand students’ opportunities for mentorship and peer-to-peer support.
With a portion of its the new HHMI grant, the University of Arizona will add to its BioMath course offerings and provide support to undergraduates doing summer research at the interface of biology and math.
Clemson University wants middle and high school students to think about going to college—and about majoring in science when they get there.
An undergraduate laboratory class called the “Python Project” teaches students about the python genome.