The biological basis of schizophrenia is not fully understood, but new research by HHMI international research scholar Michael Salter offers insights into the disruptions in brain chemistry that underlie the debilitating mental illness.
Using chemical genetics to single out a single kinase among the hundreds inside a cell, scientists have gleaned new information about how one such protein might contribute to cancer-promoting signaling.
New maps detailing where certain markers of genetic regulation are found in a variety of cell types will help researchers interpret large-scale analyses.
A zebrafish model of human melanoma has helped scientists identify new targets for potential therapies.
New research offers a genetic explanation for why some patients' lung tumors disappear almost completely when treated with the drug erlotinib, while other patients' responses are far less dramatic.
The Trustees of HHMI have elected Nitin Kotak as vice president and chief financial officer. He joins the Institute from Bethesda-based Technest Holdings, Inc.
Searching for a new food source is a big decision for a worm, based on hunger, dining companions, oxygen availability, and, according to a new study, genetics.
The 2011 prize honors Elaine Fuchs, James Thomson, and Shinya Yamanaka for pioneering work in isolating human stem cells.
Flickering black and white movies show components of the spliceosome coming and going from bits of RNA as they await processing.
The clear and watery substance that bathes the brain and spinal cord is enough to support the growth of neural stem cells in the lab.
Specific traits that distinguish humans from their closest living relatives can be attributed to the loss of chunks of DNA that control when and where genes are turned on.
With the flick of a genetic light switch, researchers have reduced symptoms of anxiety in laboratory mice.
A new genetic method for labeling cells transforms the tangles of neurons within the brain of a fruit fly into fantastic rainbows of color.
Janelia researchers create a new microscope that uses a thin sheet of light to reveal the dynamic inner life of cells.
Triple-negative tumors lack three traits that can be targeted by available breast cancer treatments. But new findings suggest treatment possibilities for these aggressive cancers may be at hand.
Gloria Tavera is a 2011 Gilliam Fellow.
Nine science students from universities across the United States are named the 2011 Gilliam Fellows.
Andria Ashmore is a 2011 Gilliam Fellow.
HHMI has doubled the number of the Gilliam Fellowships available to Ph.D.-seeking students from groups traditionally underrepresented in the sciences.
Chinweike Okegbe is a 2011 Gilliam Fellow.
Benyam Kinde is a 2011 Gilliam Fellow.
Espoir Kyubwa is a 2011 Gilliam Fellow.
Nicolas Altemose is a 2011 Gilliam Fellow.
Nadia Herrera is a 2011 Gilliam Fellow.
Jessica Cabral Jimenez is a 2011 Gilliam Fellow.
Sandra Jones is a 2011 Gilliam Fellow.
The HHMI Bulletin iPad app is now available for download in the Apple App Store.
A newly identified genetic marker appears to predict a diagnosis of post-traumatic stress disorder in women, but not in men.
Graham Walker will talk about running a science education research group and developing resources for MIT and the larger education community in a AAAS plenary talk.
A rapid new method of blocking gene function is letting researchers dissect how stem cell progenitors in the skin split their energy between creating copies of themselves and crafting specialized new cells.
A corrective strategy used by astronomers to sharpen images of celestial bodies can now help scientists see with more depth and clarity into the living brain of a mouse.
Scientists have used next-generation DNA sequencing tools to identify a mutation in a gene that underlies one of the most common forms of severe hypertension.
Neurons that control aggression and mating are closely intertwined deep within the brain.
HHMI is launching a $60 million documentary film initiative that aims to bring high quality, compelling science features to television.
Students at 12 more schools were chosen to participate in a year-long genomics course from HHMI's Science Education Alliance.
The Science Education Alliance is celebrating a major milestone with a scientific publication. The 192-author article is based on the work of students and faculty at the first 12 schools that offered its phage genomics course.
Researchers gain a new view of how genes are converted to protein by freezing the action during the earliest stage of the process.
Thirteen HHMI professors have proposed seven initiatives that they believe would improve the quality of undergraduate science education and student engagement.
Researchers at Stanford University have discovered that they may be able to tweak cancer cells so that they summon their own demise.
In mice with light-sensitive neurons in their brain, illuminating one type of neuron drives the animals to their food bowls, whereas targeting a different type makes them abstain.
Sean Carroll, vice president for science education at the Howard Hughes Medical Institute, will deliver a public lecture titled “Remarkable Creatures: Epic Adventures in the Search for the Origins of Species” at the Janelia Farm Research Campus on February 9.
After a rapid genetic analysis of bacteria collected from Haitian patients, scientists conclude that the strain of cholera currently sweeping through post-earthquake Haiti originated in South Asia.
HHMI has launched an international competition to select up to 35 early career scientists working at academic institutions in 18 countries on five continents.
A study in fruit flies shows that turning back the clock on aging muscles delays aging in the whole animal.
Safe and effective vaccines could complement efforts to treat those already infected with cholera and provide clean water and sanitation to control its spread.
A new study has pinned some of the symptoms of Rett syndrome to a set of neurons that usually work to rein in nerve cell firing in the brain.
New research suggests rising temperatures in the highlands of East Africa are at least partly to blame for the increase in malaria transmission in recent decades.
A previously overlooked group of cells has been shown to be essential in helping adult stem cells multiply and revitalize damaged tissue.
Through an international study of the genome in persons who control HIV without the need for medications, scientists have identified a handful of amino acids that seem to predict a person’s ability to successfully keep the virus in check.
Researchers have shown that radiation-resistance among tumor stem cells can be dramatically lowered by heating them up.