Interfering with communication among bacteria can prevent them from mounting a unified assault on their host.
A new study shows that most early ovarian tumors exist for years at a size that is a thousand times smaller than existing tests can detect reliably.
Un nuevo estudio muestra que la mayoría de los tumores ováricos en estadios tempranos tienen, durante años, un tamaño que es mil veces más pequeño del que los análisis existentes pueden detectar con confiabilidad.
Tiny, hair-like projections called cilia sense bitter material in the airways and help expel it.
An HHMI-funded graduate student and her colleagues have found that some chimps infected with the primate form of HIV develop AIDS-like symptoms and die early.
New clues narrow the search for the underlying cause of a serious congenital heart defect.
Brief bios of the 2009 Early Career Physician Scientists.
Eleven promising physician-scientists whose research interests range from obesity to childhood cancer will share a total of $4 million from the Howard Hughes Medical Institute.
Lung cancer cells hijack a master cellular signal and use it to seed deadly new tumors in the brain, bone marrow, and other organs.
New evidence suggests that damage to nerve cells in people with MS accumulates because the body's mechanism for repairing the nerve coating called myelin stalls out.
Researchers have identified two proteins that begin to explain how radically slashing calories leads to a longer life.
Joan Massagué honored for elucidating one of the fundamental processes that control cell division.
A new method will speed the identification of the targets of microRNAs—the tiny but powerful bits of nucleic acid that tweak gene expression to influence many aspects of health and human disease.
Friedman honored for research leading to discovery of hormone that regulates appetite and body weight.
HHMI is expanding collaborations with the Jane Coffin Childs Memorial Fund, the Helen Hay Whitney Foundation, the Damon Runyon Cancer Research Foundation, and the Life Sciences Research Foundation to increase support for outstanding postdoctoral researchers.
New research shows that a father’s sperm passes along a previously unrecognized set of instructions that helps guide the early development of his children.
A new molecular portrait of rotavirus may help researchers design more effective vaccines against the lethal gastrointestinal infection that kills 500,000 children annually.
A new microscopy technique is enabling researchers to capture videos of fast-moving cellular processes with super high resolution.
Additional housing will be constructed on the Janelia Farm Research Campus to support the recruitment of graduate students, postdoctoral researchers, and other scientists at the beginning of their careers.
New research indicates that in most cases, natural selection may shape the human genome much more slowly than previously thought.
The report "Scientific Foundations for Future Physicians" lays out a series of scientific competencies that students must master prior to attending medical school and medical students must understand upon completion of their MD.
A new report for the first time defines scientific competencies for future medical school graduates and for undergraduate students who want to pursue a career in medicine.
HHMI researchers identify many potential new drug targets for cancers long deemed "untouchable."
HHMI will hold its third nationwide competition to find 12 colleges and universities to join the Science Education Alliance, a bold effort to engage students through authentic research experiences at the start of their academic careers.
Mississippi high school teachers have teamed up with scientists at the University of Mississippi Medical Center and the Marine Biological Laboratory to design a high school biology curriculum focused on fire ants.
Research suggests new avenues to treat or prevent infections by parasitic worms.
A protein often accused of sparking autoimmune disease can suppress the onset of inflammatory bowel disease.
HHMI scientists have taken a major step towards understanding the molecular mechanisms that transform Listeria monocytogenes from a harmless soil-dweller to a dangerous human pathogen by mapping the genes that Listeria expresses under different environmental conditions.
Former Trustee served HHMI for 18 years, helping shape the Institute's research programs.
Horvitz's election to the Fellowship of the Royal Society recognizes his exceptional contributions to science.
Ultraviolet radiation from the sun can zap DNA, damage cells, and set the stage for the subsequent development of cancer. Scientists have now identified the built-in safety mechanism that forces some cells damaged by UV radiation to commit suicide so they do not perpetuate harmful mutations.
La radiación ultravioleta del sol puede destruir el ADN, dañar las células y predisponer al organismo para el desarrollo subsecuente de cáncer. Unos científicos han identificado el mecanismo de seguridad intrínseco que fuerza a algunas células dañadas por la radiación UV a cometer suicidio para no perpetuar mutaciones dañinas.
The movement of blood through the aorta of a developing embryo triggers the production of new blood stem cells.
On June 9, HHMI investigator Ron Evans will deliver a public talk, "Unlocking Ability: What Can Research Teach Us About Exercise?"
Scientists have identified a protein that hampers learning and memory by keeping DNA inside neurons tightly coiled.
HHMI President Robert Tjian is among those elected to the eminent scholarly organization.
As the academic year winds down, 112 medical, dental, and veterinary students are preparing to meet a new challenge: A year in a laboratory that will hone their scientific skills and prepare them for possible careers in research.
Genetic clues suggest how invasive breast cancer cells pry their way into the tightly protected interior of the brain.
With the emergence of a new strain of influenza A(H1N1), scientists have a unique opportunity to study viral evolution in action.
The pulsing of a single neuron can switch a brain’s waves from the equivalent of a big ocean swell to ripples on a pond.
La pulsación de una sola neurona puede cambiar las ondas cerebrales de forma equivalente a lo que sería transformar las ondas del oleaje marino en las pequeñas ondas que se pueden observar en una laguna.
Ten scientists affiliated with the Howard Hughes Medical Institute have been elected to the National Academy of Sciences.
Eight HHMI scientists and one HHMI scientific review board member are among 210 fellows and 19 foreign honorary members elected.
A new strategy for generating plug-and-play components could make life easier for synthetic biologists.
Two critical genes that serve as beacons and give cells a much needed sense of direction in the chaotic days of early development have been identified by HHMI researchers at the University of Toronto.
HHMI will challenge research universities to develop compelling new ways to show undergraduate students the excitement and creativity of science by inviting nearly 200 top institutions to compete for individual grants of up to $2.2 million. HHMI plans to award up to $85 million in total grants.
A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs.
HHMI researchers have designed tiny RNA molecules that shut off the gene that causes Huntington’s disease without damaging that gene’s healthy counterpart, which maintains the health and vitality of neurons.
An international scientific challenge is being launched to speed development of new tools that accurately and automatically reconstruct the shape of brain cells from microscopy data.