Researchers have a new understanding of how sperm and eggs begin life with exactly one copy of each chromosome.
Patients with multiple sclerosis carry a population of immune cells that over-react to Epstein-Barr virus.
Researchers have identified a protein that reins in the rogue activity of the molecules that make the amyloid-beta protein, which may prevent normal brain function in people with Alzheimer's disease.
Five current HHMI investigators, one trustee of the Institute, one member of the Institute's scientific review board, and one HHMI international research scholar were among those honored.
Seven HHMI investigators, along with an HHMI professor, an international research scholar, and a member of the scientific review board are elected to the academy.
Researchers have created a mouse model that closely mimics the most common childhood brain tumor.
HHMI research shows that evolution is an incessant tinkerer when it comes to complex traits.
Researchers have discovered the first African hantavirus, a type of rodent-borne virus that can cause life-threatening infections in humans.
A change in a single gene may be in large part responsible for the evolution of flight in bats.
Researchers find new clues to why some kinds of leukemia are more aggressive and deadly than others.
A common blood pressure medication may help prevent potentially deadly complications of Marfan syndrome.
Cells use specialized segments of RNA to ensure that there is an adequate supply of magnesium.
Una medicación comúnmente prescrita para la presión sanguínea puede proporcionar el primer atisbo de esperanza para la prevención de las complicaciones potencialmente mortales del síndrome de Marfan, una enfermedad genética que debilita la intrincada estructura de vasos sanguíneos.
Researchers have identified a gene mutation that weakens small blood vessels, increasing the danger of stroke.
Joan A. Steitz and Ronald M. Evans have received the Gairdner International Award.
New research indicates there is a useful difference between cells that keep the blood system healthy and the stem cells that make leukemia lethal.
Scientists have traced female fruitflies' complex behavioral change after mating to a single protein in the semen of males.
HHMI researchers have discovered a new retrovirus in humans that is closely related to a cancer-causing virus found in mice.
Enzymes that can harm the brain immediately after a stroke may actually be beneficial days later.
Sustained over the long term, a decrease in low density lipoprotein (LDL) cholesterol of as little as 15 percent can dramatically reduce the risk of coronary heart disease.
Researchers have mathematically confirmed that humpback whales have their own syntax that combines sounds into phrases to form songs that last for hours.
HHMI researchers have demonstrated that they can nearly eliminate production of infectious prion proteins in livestock by using an innovative approach based on RNA interference (RNAi).
A new color-changing tag based on the light produced by a variety of sea coral could help scientists follow individual proteins inside living cells.
An HHMI research team has identified the cellular receptor for botulinum neurotoxin A.
Equipo de investigadores del HHMI identifica el receptor celular de la toxina botulínica A.
A rare opportunity to study patients with an intractable form of epilepsy leads to the discovery of specific neurons in the human brain that respond to novel or familiar objects.
Researchers studying strains of a lethal canine virus and a related human virus have determined why the canine virus was able to spread so quickly from cats to dogs and then from sick dogs to healthy dogs.
Researchers in Argentina have determined that night blindness is a new clinical symptom of Chagas disease.
Using computer-simulated HIV protease molecules, scientists have identified a potential new drug target for drug-resistant HIV infection.
Investigadores de Argentina han determinado que la ceguera nocturna es un nuevo síntoma clínico de la enfermedad de Chagas.
Using laundry whitener and dirt-dwelling bacteria, researchers may have found a major clue to the mystery of how living organisms manufacture the essential vitamin B12.
The virus that has a causative role in Kaposi's sarcoma hitchhikes inside cells to ensure its survival.
A new study by HHMI researchers shows that macrophages may also permit prostate cancer to flourish.
Researchers have gained insight into how a wriggling sperm thrusts itself into an egg.
An innovative method of categorizing myosin, one of three molecular motors that produce movements within cells of the body, had dramatically increased the amount of information available about these essential proteins.
Scientists have determined the structure of an essential piece of the telomerase enzyme.
Científicos determinan la estructura detallada de una pieza esencial de la enzima telomerasa, importante contribuidora de la gran mayoría de los cánceres humanos. La comprensión de la forma física de la proteína ha llevado a un mejor entendimiento de la forma en la que inmortaliza las células –y debería ayudar a los científicos a diseñar drogas contra el cáncer que sean ampliamente eficaces–.
Neuroscientists at Harvard Medical School have found a molecule that the brain uses to slam the brakes on daily activity at certain times.
Scientists in India led by an HHMI international research scholar have identified five key genes that enable the bacteria that cause TB to acquire the iron they need to promote infection.
Científicos de la India, conducidos por un becario internacional de investigación del HHMI, identifican cinco genes claves que permiten que la bacteria que causa la tuberculosis adquiera el hierro que necesita para mantener el crecimiento y promover la infección.
Knocking out a gene that helps repair nicks in DNA causes young mice to develop many of the degenerative characteristics of their wizened elders.
HHMI scientists and colleagues at Johns Hopkins have found a critical clue that helps explain what goes wrong in a key region of the brain at the onset of Down syndrome.
An HHMI international scholar at the Pasteur Institute in Paris has found the malaria parasite developing in an unexpected place: the lymph nodes.
Becario internacional de investigación del HHMI en el Instituto Pasteur de París encuentra que los parásitos de la malaria se desarrollan en un lugar inesperado: los nódulos linfáticos.