HHMI researchers have developed a mouse model of osteosarcoma, the most common form of bone cancer.
A new model reveals that three classes of HIV drugs inhibit the virus more than 10,000 times better than others
Nuevo modelo matemático revela que tres clases de drogas contra el VIH inhiben al virus 10.000 veces mejor que otras.
Researchers have identified a chemical messenger that helps different sites on individual neurons coordinate with one another.
Scientists have demonstrated how protocells might have taken up nutrients from the earth's early environment to propel their growth.
Scientists have discovered that the mutation that causes Rett syndrome interferes with the regulation of 2,500 other genes.
A protein previously thought to identify only colon cancer stem cells is actually prevalent throughout primary colon tumors.
A prominent protein on the surface of liver cells protects organisms during sepsis, one of the most common and deadly side effects of bacterial infection.
HHMI researchers bring the arcane world of protein folding to the online gaming arena with the launch of "Foldit."
Investigadores del HHMI acercan el arcano mundo del plegamiento proteico al terreno de juegos en Internet con el lanzamiento de “Pliégalo”.
Researchers have produced the first high-resolution map showing the structural variation that exists in the human genome.
A mutant RNA may be partially to blame for the neurodegeneration associated with spinocerebellar ataxia type 3.
Vision has improved in all three patients who have received gene therapy for a rare but severe form of retinal degeneration.
Just three years after discovering a genetic mutation that causes a trio of leukemias, HHMI researchers have helped move a new leukemia drug into clinical trials.
HHMI researchers identify rare mutations in three genes that contribute to blood pressure variation in the general population.
Investigadores del HHMI han encontrado que mutaciones raras en tres genes contribuyen a variaciones en la presión arterial de la población general.
A new picture of a genetic parasite is helping researchers see how specialized segments of RNA escape from their positions in the genome and invade new ones.
New studies provide a fresh view of the computational power of neurons.
Researchers have identified hundreds of genes that keep embryonic stem cells in their characteristic malleable state.
Researchers have designed and built two functional enzymes never seen in nature.
Con la ayuda de la donación de tiempo computacional de miles de personas en todo el mundo, Investigadores del HHMI han diseñado y construido dos enzimas funcionales nunca antes vistas en la naturaleza.
A cellular gatekeeper inside a malaria parasite doesn't care whether the amino acid letters on a protein's entry ticket are out of order.
Researchers studying spinocerebellar ataxia have uncovered a pathological mechanism that may also underlie more common neurological diseases.
HHMI announces a major new program that will provide much-needed support to some of the nation's best early career faculty.
View the complete list of eligible institutions.
Metastatic colon cancers carry the ability to metastasize from the time they become cancerous, and don't need to acquire any new genetic mutations to become metastatic.
A fruit fly's misguided neurons provide a fascinating look at the evolution of systems that detect carbon dioxide.
People who lack a certain large segment of DNA have a previously unrecognized syndrome characterized by mental retardation, seizures, and slight physical abnormalities.
HHMI researchers have developed novel techniques and software that will provide scientists with the tools they need to decipher large-scale patterns in the vital - but little-understood - process of DNA methylation.
Investigadores del HHMI han desarrollado técnicas y software nuevos que les proveerán a los científicos de las herramientas necesarias para descifrar patrones de metilación a gran escala en el vital –pero poco entendido– proceso de metilación de ADN.
Malaria-causing parasites evade the immune system by ducking in and out of cells.
Certain regions inside the nucleus can prevent the genes inside them from becoming activated.
HHMI researchers have uncovered a protein that stops the growth of melanoma.
A new microscopy technique allows researchers to examine the complete three-dimensional morphology of many of the tiniest structures of cells.
Investigadores del HHMI descubren una proteína que detiene el crecimiento del melanoma.
A study that examined the activity of one plant species' 22,000 genes over a complete day and night cycle showed that midnight is a special time that plants can actually distinguish.
HHMI investigators are beginning to examine every gene in the genome to figure out which genes are deleterious to tumor cells.
The birth of new neurons appears to facilitate certain types of complex learning.
HHMI researchers have revealed how a molecule-munching enzyme helps maintains the internal highways found in cells.
The body's immune system can use a surprisingly common molecule to recognize prostate tumors.
Researchers have identified 273 host proteins that serve to keep the AIDS virus healthy and happy as it infects cells.
Researchers have identified small pieces of RNA that suppress the spread of breast cancer to the lungs and bone.
New research has found that many of the symptoms of fragile X syndrome can be eliminated in mice by reducing the expression of a single gene.
Researchers have a new picture of how neurons forge physical connections between one another in order to communicate.
Even short bursts of activity in a few neurons can influence learning and decision making.
New findings help explain how the brain communicates with the inner ear, reducing its response to sound in loud or distracting environments.
Nuevo descubrimiento ayuda a explicar cómo se comunica el cerebro con el oído interno, reduciendo la respuesta al sonido en ambientes ruidosos o que distraen.
Despite a vast evolutionary gulf, humans and the three-spined stickleback fish have adopted a common genetic strategy to acquire the skin pigmentation that helps them thrive.
A team of researchers has exposed how one of the genes most commonly mutated in human cancers helps good cells go bad.
A pesar de la gran brecha evolutiva que existe entre los seres humanos y el pez espinoso de tres espinas, las dos especies han adoptado una estrategia genética común para adquirir la pigmentación de la piel que ayudaría a estas dos especies a prosperar en su nuevo ambiente.