Molecular studies of a family of genes are pruning branches from the old evolutionary tree.
Genetic studies confirm that one gene mutation plays a major role in inherited deafness; the importance of another genetic mutation is called into question.
HHMI researchers discover a gene responsible for triggering embryonic cells in the inner ear to develop into sound- and motion-sensing hair cells.
HHMI researchers have found a protein whose activity controls the shape of a developing organ.
HHMI invites colleges, universities to compete for $48 million to enrich undergraduate science education.
HHMI researchers have discovered a molecule that resembles a component of snake toxins, but has a dramatically different effect on the nervous system.
Conference in Moscow on June 22-25 to feature International Research Scholars from 10 countries. Read about it in English or Russian.
HHMI to award $14 million through new international initiative to combat diseases with worldwide impact.
HHMI to award $15 million to support biomedical research in the Baltics, Central and Eastern Europe and the former Soviet Union.
Howard Hughes Medical Institute Awards $1.32 Million to Cold Spring Harbor Laboratory for Short Courses
Four-year grant will support 12 advanced courses on topics such as parasitism, embryology, microbial diversity and cell signaling.
Nitric oxide prevents programmed cell death by handcuffing the molecular executioner.
A new grant opens NIH internships to science teachers throughout the Washington, D.C. area.
HHMI's Trustees have announced that Thomas R. Cech of the University of Colorado at Boulder will become the next president of the Institute.
Studies of a molecule that causes severe weight loss in cancer patients may yield new drugs to treat obesity.
Two HHMI labs discover a new molecular road sign that directs axons to their proper destination in the central nervous system.
HHMI researchers find that the mahogany protein suppresses obesity and plays a role in the immune system.
With odorant receptor genes from Drosophila in hand, researchers hope to learn how odors influence behavior.
How does the nose discriminate between different odors?
HHMI researchers have developed a versatile method for improving binding properties of potential drugs.
HHMI researchers have identified a gene that influences formation of the chambers of the heart.
Mouse geneticists get a boost with the release of an encyclopedia containing more than 360,000 genetic sequences.
By studying flies that have mutations similar to some cancer patients, HHMI researchers have found a new type of tumor suppressor gene.
HHMI's International Research Scholars from six countries in the Americas gathered in Rio de Janeiro for a scientific conference. Special Web reports covered the event while it was happening.
Dopamine transporter knockout mice developed by HHMI investigator Marc Caron and colleagues have provided a wealth of information about the molecular nature of some behavioral disorders.
A human cell surface protein that maintains the structural integrity of tissues is also the portal of entry for bacteria and viruses.
HHMI investigators have produced an image of the active form of the HIV enzyme reverse transcriptase. This work may clarify how mutations render HIV resistant to antiviral drugs.
A team of scientists from the Howard Hughes Medical Institute at the University of Chicago has found that a ubiquitous protein may explain how relatively sudden changes in body shape occur in a species.
Un equipo de científicos del Instituto Médico Howard Hughes en la Universidad de Chicago ha encontrado que una ubicua proteína puede explicar cómo se llevan a cabo los cambios relativamente repentinos en la forma del cuerpo de una especie.
The most common genetic cause of infant mortality happens because cells cannot properly process messenger RNA. The search for drugs to correct this defect is underway.
Conference in Rio on January 19-22 to feature International Research Scholars from six countries in the Americas.
Christine E. Seidman and Richard P. Lifton will discuss the genetics of cardiovascular disease and the role of the kidney in hypertension at HHMI's annual lecture series for high school students and other viewers.
HHMI investigators have found a cellular target of survival signals that can override programmed cell death.
Genetic studies have uncovered a host of new genes involved in the formation of spores in yeast. The studies may illuminate germ cell production in vertebrates.
HHMI researcher Leonard Zon leads a team that has cloned a zebrafish anemia gene, producing one of the first fish models of a human disease. The achievement opens a new avenue for studying the genetics of human diseases.
Grants will help selected institutions to sustain their critical biomedical research activities amid major changes in the U.S. health care system.
HHMI researchers show that ribozymes and enzymes are ready to perform their biological function as soon as they are produced.
HHMI selects young physicians to receive support to train as physician-scientists.
$800,000 HHMI grant will enable JSTOR to offer online access to all past issues of Science, the Proceedings of the National Academy of Sciences and other journals.
The tumor suppressor p16 normally holds the growth-promoting molecule Cdk6 in check. New structural insights may explain how Cdk6 slips free from p16, promoting cancer development.
HHMI researchers produce the first glimpses of the molecular machinery that propels neurotransmitters into the synapse.
New HHMI Web site provides hands-on activities for elementary school students.
Purnell W. Choppin, president of the Howard Hughes Medical Institute, has announced that he will retire at the end of 1999.
More than $425 million awarded since 1988 to revitalize undergraduate biological sciences education.
HHMI investigators have found another molecular landmark that points growing neurons to their proper destination in the brain or spinal cord.
Researchers report the first hard evidence that most cases of colon cancer arise when mutations in a genetic "master brake" help to switch on a well-known cancer-promoting gene.
Researchers used to identify important developmental genes one at a time. Now, a technique developed in Drosophila is taking wing, and hundreds of novel genes have been found.
Researchers find that a drug used to treat adult-onset diabetes may promote the formation of colorectal tumors.
The human immune system can recognize and destroy thousands of invaders. Did this diversity come about accidentally when a mobile piece of DNA inserted itself into the mammalian genome more than 450 million years ago?
Researchers discover new details about how cells monitor the signals that stimulate proliferation or shut down cell growth. Such signals can turn a normal cell into one that grows uncontrollably, the first step in the development of cancer.