HHMI researchers have determined the three-dimensional structure of invasin, a protein that allows a close relative of the bubonic plague bacterium to infect intestinal cells and cause food poisoning.
The creek becomes a classroom for California youngsters. Grants in Action.
By studying five generations of a Maine family, HHMI researchers have learned how an inherited leukemia develops.
HHMI researchers develop a new class of molecules that can prevent HIV infection of human cells.
A 14-year search for the genetic mutations that trigger a neurodegenerative disease has ended.
A unique hemoglobin is key to a parasitic worm's ability to survive in a world containing oxygen.
New antiviral compounds may prevent HIV infection of cells by disrupting the protein gp41.
A gene crucial to C. elegans mating behavior resembles a gene involved in polycystic kidney disease.
HHMI investigators say that stem cells may prove to be better than viruses for delivering corrective genes to tissues throughout the body.
HHMI investigators have found a gene that determines whether roundworms prefer to eat alone or in a group. Further studies may give a glimpse at the genetic origins of social behavior.
HHMI researchers are making fundamental advances in understanding how genes control the shape and spatial orientation of organs.
Scientists have uncovered a critical mechanism by which light resets the biological clock in flies. This finding could lead to new treatments for jet lag and improved therapies for mood and sleep disorders.
HHMI researchers have used a fragment of HIV to deliver proteins into the cells of living mice.
Two related proteins that act as brakes for a variety of cellular growth processes appear to play a critical role in ensuring that both blood cells and immune system cells are neither overactive nor overabundant.
Teen tackles English, scores a Rhodes Scholarship. Grants in Action.
HHMI researchers have found the first hereditary human sleep disorder that is caused by a single gene. The disorder is passed from generation to generation in the same simple pattern characteristic of traits such as eye color.
HHMI researchers believe their technique can be used to determine the function of all of the fruit fly's genes.
A team of biologists has determined the three-dimensional structure of an enzyme that allows certain bacteria to resist the killing effects of the antibiotic gentamicin. The structure is also shared by a number of proteins involved in basic biological processes, including circadian rhythms and gene regulation.
A genetic mutation common in the most severe forms of muscular dystrophy also predisposes to heart damage.
Two genes that generate the immune system's remarkable diversity are controlled by the same small piece of DNA.
Mice born without a gene that regulates appetite exhibit unexpected attacks of narcolepsy.
A two-tiered boost to the immune system may allow the body to better fight cancer on its own.
Cancer research captivates high schooler in HHMI-funded Student and Teacher Program at NIH. Grants in Action
New theories about how neural activity and visual stimuli sculpt the developing visual system.
VectorNet enables students and teachers to analyze their own DNA sequences and DNA sequences from the Human Genome Project, which are posted in databases on the Internet.