HHMI researchers have developed a versatile method for improving binding properties of potential drugs.
HHMI researchers have identified a gene that influences formation of the chambers of the heart.
Mouse geneticists get a boost with the release of an encyclopedia containing more than 360,000 genetic sequences.
By studying flies that have mutations similar to some cancer patients, HHMI researchers have found a new type of tumor suppressor gene.
HHMI's International Research Scholars from six countries in the Americas gathered in Rio de Janeiro for a scientific conference. Special Web reports covered the event while it was happening.
Dopamine transporter knockout mice developed by HHMI investigator Marc Caron and colleagues have provided a wealth of information about the molecular nature of some behavioral disorders.
A human cell surface protein that maintains the structural integrity of tissues is also the portal of entry for bacteria and viruses.
HHMI investigators have produced an image of the active form of the HIV enzyme reverse transcriptase. This work may clarify how mutations render HIV resistant to antiviral drugs.
A team of scientists from the Howard Hughes Medical Institute at the University of Chicago has found that a ubiquitous protein may explain how relatively sudden changes in body shape occur in a species.
Un equipo de científicos del Instituto Médico Howard Hughes en la Universidad de Chicago ha encontrado que una ubicua proteína puede explicar cómo se llevan a cabo los cambios relativamente repentinos en la forma del cuerpo de una especie.
The most common genetic cause of infant mortality happens because cells cannot properly process messenger RNA. The search for drugs to correct this defect is underway.
Conference in Rio on January 19-22 to feature International Research Scholars from six countries in the Americas.
Christine E. Seidman and Richard P. Lifton will discuss the genetics of cardiovascular disease and the role of the kidney in hypertension at HHMI's annual lecture series for high school students and other viewers.
HHMI investigators have found a cellular target of survival signals that can override programmed cell death.
Genetic studies have uncovered a host of new genes involved in the formation of spores in yeast. The studies may illuminate germ cell production in vertebrates.
HHMI researcher Leonard Zon leads a team that has cloned a zebrafish anemia gene, producing one of the first fish models of a human disease. The achievement opens a new avenue for studying the genetics of human diseases.
Grants will help selected institutions to sustain their critical biomedical research activities amid major changes in the U.S. health care system.
HHMI researchers show that ribozymes and enzymes are ready to perform their biological function as soon as they are produced.
HHMI selects young physicians to receive support to train as physician-scientists.
$800,000 HHMI grant will enable JSTOR to offer online access to all past issues of Science, the Proceedings of the National Academy of Sciences and other journals.
The tumor suppressor p16 normally holds the growth-promoting molecule Cdk6 in check. New structural insights may explain how Cdk6 slips free from p16, promoting cancer development.
HHMI researchers produce the first glimpses of the molecular machinery that propels neurotransmitters into the synapse.
New HHMI Web site provides hands-on activities for elementary school students.
Purnell W. Choppin, president of the Howard Hughes Medical Institute, has announced that he will retire at the end of 1999.
More than $425 million awarded since 1988 to revitalize undergraduate biological sciences education.