Genetic studies have uncovered a host of new genes involved in the formation of spores in yeast. The studies may illuminate germ cell production in vertebrates.
HHMI researcher Leonard Zon leads a team that has cloned a zebrafish anemia gene, producing one of the first fish models of a human disease. The achievement opens a new avenue for studying the genetics of human diseases.
Grants will help selected institutions to sustain their critical biomedical research activities amid major changes in the U.S. health care system.
HHMI researchers show that ribozymes and enzymes are ready to perform their biological function as soon as they are produced.
HHMI selects young physicians to receive support to train as physician-scientists.
$800,000 HHMI grant will enable JSTOR to offer online access to all past issues of Science, the Proceedings of the National Academy of Sciences and other journals.
The tumor suppressor p16 normally holds the growth-promoting molecule Cdk6 in check. New structural insights may explain how Cdk6 slips free from p16, promoting cancer development.
HHMI researchers produce the first glimpses of the molecular machinery that propels neurotransmitters into the synapse.
New HHMI Web site provides hands-on activities for elementary school students.
Purnell W. Choppin, president of the Howard Hughes Medical Institute, has announced that he will retire at the end of 1999.
More than $425 million awarded since 1988 to revitalize undergraduate biological sciences education.
HHMI investigators have found another molecular landmark that points growing neurons to their proper destination in the brain or spinal cord.
Researchers report the first hard evidence that most cases of colon cancer arise when mutations in a genetic "master brake" help to switch on a well-known cancer-promoting gene.
Researchers used to identify important developmental genes one at a time. Now, a technique developed in Drosophila is taking wing, and hundreds of novel genes have been found.
Researchers find that a drug used to treat adult-onset diabetes may promote the formation of colorectal tumors.
The human immune system can recognize and destroy thousands of invaders. Did this diversity come about accidentally when a mobile piece of DNA inserted itself into the mammalian genome more than 450 million years ago?
Researchers discover new details about how cells monitor the signals that stimulate proliferation or shut down cell growth. Such signals can turn a normal cell into one that grows uncontrollably, the first step in the development of cancer.
A powerful, award-winning video that encourages minority students to pursue careers is now available on the Web.
Meeting Features Leading Biomedical Scientists From Central Europe, Former Soviet Union and the Baltics
Salt is poison for people with high blood pressure. Genetic studies are beginning to clarify who is at risk and why.
Scientists Determine Structure of HIV-1 Protein that Grasps Human Cells.
Researchers have identified a faulty conduit into nerve cells that causes them to fire uncontrollably, triggering the brief seizures that characterize some forms of epilepsy.
eCircadian clocks maintain the sleep-wake cycle for a 24-hour day in a variety of organisms. Two HHMI researchers and their colleagues have discovered more of the clock's molecular components.
Hughes investigators have discovered a family of packemaker ion channels that power the heart and the brain