New studies highlight promising vaccine strategies to prevent malaria parasites from causing illness and death.
Horwich and Franz-Ulrich Hartl share the 2011 Albert Lasker Basic Medical Research Award for key discoveries that elucidate steps in protein folding.
Scientists have identified a genetic regulator that controls the reshuffling of gene segments in immune cells.
Beachy is being honored for his work on Hedgehog, a key molecule in development.
HHMI researchers have developed a potential TB vaccine that completely eliminates tuberculosis bacteria from infected tissues in some mice.
Distinct areas of the brain process sweet, bitter, salty, and umami tastes.
Designer ion channels that can turn neurons on or off will help researchers understand the connection between behavior and neural circuitry.
The first definitive proof of a weak spot in the parasite's apicoplasts—organelles with ancient plant origins—offers hope for drugs and vaccines against malaria.
New research has classified vertebrate evolution in relation to periods of evolution marked by changes in specific kinds of genes.
Protective chemicals known as interferons may identify themselves by how tightly they grip their receptor at various attachment points.
An HHMI-funded researcher has used online gene expression profiles to match old drugs with diseases in need of treatments.
Next-generation sequencing and stem cell technology have helped scientists identify a mutation that causes retinitis pigmentosa.
Understanding of antibody may help scientists design a longer-lasting vaccine against the influenza virus.
A new fellowship program will enable 48 graduate students from 22 countries to devote their full attention to research at a critical time during their professional development as scientists.
Nuevo programa de becas permitirá que 48 estudiantes de postgrado de 22 países dediquen toda su atención a la investigación en un momento crítico de su desarrollo profesional como científicos.
A test that detects a cancer-causing fusion gene in men’s urine could help reduce the number of prostate biopsies performed each year.
Two studies reveal genetic mutations often present in the most common form of head and neck cancer, offering a picture of how the cancer develops and how therapeutics could treat it.
A genetic comparison of E. coli strains, including the one responsible for the recent outbreak of infections in Europe, underscores how rapidly evolving bacterial genomes can lead to the emergence of new pathogens.
Altering the balance of excitatory and inhibitory inputs in the brains of mice disrupts the animals' social interactions.
The neurological problems caused by Fragile X syndrome may be due to excess synthesis of certain proteins.
An immune defense protein uses prion-like qualities to fend off viruses.
Small bits of RNA can cause a connective tissue cell from human skin to transform into a nerve cell.
Distinguished cell biologist is named first editor of a new journal that HHMI, the Max Planck Society, and the Wellcome Trust will launch next year.
Medical, dental, and veterinary students from 47 schools will be diving into intensive, HHMI-sponsored research experiences this summer at top research centers across the country.
The Howard Hughes Medical Institute, the Max Planck Society, and the Wellcome Trust will support a new journal that will aim to attract and define the very best research publications from across these fields.