HHMI scientists at the University of Texas Southwestern Medical Center are blocking the enzyme telomerase in a new strategy to prevent cancer cells from dividing.
Don Ganem's decision to search for a viral cause for Kaposi's sarcoma was considered risky by many molecular biologists.
Sharon Long's studies of signal transduction pathways in plants could yield insights into cancer and other diseases in humans.
Hughes researchers have developed a technique that may speed the identification of more tumor suppressor genes.
Changes in the health care system are leading some young physicians to reexamine their plans for combining research and clinical practice.
International research scholar Alec Jeffeys believes that radiation leaked from Chernobyl more than a decade ago may only now be manifesting its diastrous legacy.
Students at Texas Tech University are co-authors on a Nature paper showing a high rate of genetic change in rodents living near the Chernobyl reactor.
HHMI investigator Michael J. Welsh's research team has found that the airways of CF patients lack a natural substance that kills bacteria.
Hughes investigator Ronald D. Vale's research provides fresh insight into the structure and operation of the motor proteins that convert chemical energy in the cell into physical movement.
Experiments by Marc Caron and colleagues reveal the importance of the dopamine transporter in conditions such as addiction, schizophrenia and Parkinson's disease.
The discovery of a common genetic circuit for limb formation in arthropods is not only important for developmental biology, but also holds promise as an important new window to the past.
The Institute's Trustees accepted Helen K. Copley's resignation at their November meeting. Copley was one of the original group of Trustees appointed by the Delaware Court of Chancery in 1984.
Genes and partial gene sequences are being found at a rate far faster than anyone can decipher their function. Two groups of Hughes researchers have been attacking that bottleneck with automated programs designed to shed light on the function of newly found genes and the expression patterns of known genes.
Peter S. Kim, an HHMI investigator at the Whitehead Institute for Biomedical Research, believes that the coiled-coil structure of a protein may provide HIV with the spike it needs to infect cells.
James A. Baker, III, secretary of state under George Bush and secretary of the treasury under Ronald Reagan, has been elected a Trustee of HHMI.
HHMI investigator Kevin P. Campbell, HHMI associate Franck Duclos and University of Iowa College of Medicine M.D./Ph.D. student Leland Lim have identified a new form of muscular dystrophy and developed a screening test to detect carriers of the disease.
Daniel E. Goldberg and colleagues have discovered how the malaria parasite is able to safely sidestep a poison in hemoglobin, its main food source.